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  2. LYAR - Ly1 antibody reactive Gene

LYAR - Ly1 antibody reactive Gene

中文名称:Ly1 抗体反应性

种属: Homo sapiens

同用名: ZLYAR; ZC2HC2

基因 ID: 55646 | 基因类型: protein coding

关于 LYAR

Cytogenetic location: 4p16.3 Genomic coordinates (GRCh38): 4:4,267,701-4,290,154 (from NCBI)

This gene has 4 transcripts (splice variants) and 206 orthologues. Broad expression in testis (RPKM 46.8), lymph node (RPKM 8.5) and 20 other tissues.

功能概要

启用多种功能,包括 DNA 结合转录因子结合活性;相同的蛋白质结合活性;和转录调节抑制剂活性。参与几个过程,包括红细胞发育;先天免疫反应的负调节;和转录调控,DNA 模板化。位于核仁和核质中。 [由基因组资源联盟提供,2022 年 4 月]

Enables several functions, including DNA-binding transcription factor binding activity; identical protein binding activity; and transcription regulator inhibitor activity. Involved in several processes, including erythrocyte development; negative regulation of innate immune response; and regulation of transcription, DNA-templated. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

LYAR 基因产物(2)

mRNA Protein Name
NM_001145725.2 NP_001139197.1 cell growth-regulating nucleolar protein
NM_017816.3 NP_060286.1 cell growth-regulating nucleolar protein

LYAR 蛋白结构

zf-LYAR

zf-LYAR: LYAR-type C2HC zinc finger (31 - 58)

  • 0
  • 100
  • 200
  • 300
  • 379 a.a.
蛋白主名 其他名称

cell growth-regulating nucleolar protein

Ly1 antibody reactive homolog

LYAR 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
LYAR Q9NX58 BEND7 Homo sapiens Q8N7W2-2
Validated Y2H
25416956
种属内
LYAR Q9NX58 BEND7 Homo sapiens Q8N7W2-2
Y2H Prey Pooling
25416956
种属内
LYAR Q9NX58 SDCBP2 Homo sapiens Q9H190
Y2H Array
25416956
种属内
LYAR Q9NX58 PRKRA Homo sapiens O75569
Y2H
21516116
种属内
LYAR Q9NX58 SDCBP2 Homo sapiens Q9H190
Y2H Array
32296183
种属内
LYAR Q9NX58 PRKRA Homo sapiens O75569
Y2H Prey Pooling
25416956
种属内
LYAR Q9NX58 SDCBP2 Homo sapiens Q9H190
Validated Y2H
25416956
种属内
LYAR Q9NX58 FBL Homo sapiens P22087
Anti Bait CoIP
17353931
种属内
LYAR Q9NX58 PRKRA Homo sapiens O75569
Y2H Array
25416956
种属内
LYAR Q9NX58 SDCBP2 Homo sapiens Q9H190
Y2H Array
31515488
种属内
LYAR Q9NX58 SDCBP2 Homo sapiens Q9H190
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Neuroblastoma

Nb

Neuroblastoma, Susceptibility To

Neuroblastomas

Central Neuroblastoma

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus LYAR RGD RGD:1305352
Felis catus LYAR VGNC VGNC:63336
Mus musculus LYAR MGD MGI:107470
Bos taurus LYAR VGNC VGNC:31095
Macaca mulatta LYAR VGNC VGNC:74364
Canis familiaris LYAR VGNC VGNC:42879