KIZ - kizuna centrosomal protein Gene

中文名称：kizuna 中心体蛋白

种属: Homo sapiens

同用名: RP69; HT013; Kizuna; PLK1S1; C20orf19; NCRNA00153

基因 ID: 55857 | 基因类型: protein coding

关于 KIZ

Cytogenetic location: 20p11.23 Genomic coordinates (GRCh38): 20:21,125,975-21,246,622 (from NCBI)

This gene has 15 transcripts (splice variants), 179 orthologues and is associated with 3 phenotypes. Broad expression in testis (RPKM 20.1), ovary (RPKM 11.1) and 25 other tissues.

功能概要

由该基因编码的蛋白质定位于中心体，在纺锤体形成之前加强和稳定中心粒周围区域。编码的蛋白质通常在中心体复制后保留在母中心体中。已发现该基因编码不同亚型的几种转录物变体。[RefSeq 提供，2013 年 2 月]

The protein encoded by this gene localizes to centrosomes, strengthening and stabilizing the pericentriolar region prior to spindle formation. The encoded protein usually remains with the mother centrosome after centrosomal duplication. Sevral transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]

KIZ 基因产物(7)

mRNA	Protein	Name
NM_001163022.3	NP_001156494.1	centrosomal protein kizuna isoform 2
NM_001163023.3	NP_001156495.1	centrosomal protein kizuna isoform 3
NM_001276389.2	NP_001263318.1	centrosomal protein kizuna isoform 4
NM_001352434.2	NP_001339363.1	centrosomal protein kizuna isoform 5
NM_001352435.2	NP_001339364.1	centrosomal protein kizuna isoform 6
NM_001352436.2	NP_001339365.1	centrosomal protein kizuna isoform 7
NM_018474.6	NP_060944.3	centrosomal protein kizuna isoform 1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	16980960	GOA
enables protein kinase binding	IPI IPI: 通过物理相互作用推断	16980960	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in spindle organization	IMP IMP: 通过突变表型推断	16980960	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in centrosome	IDA IDA: 通过直接分析推断	16980960	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

centrosomal protein kizuna

polo-like kinase 1 substrate 1

KIZ 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	KIZ	Q2M2Z5	TFIP11	Homo sapiens	Q9UBB9	Y2H Array	32296183
种属内	KIZ	Q2M2Z5	TFIP11	Homo sapiens	Q9UBB9	Y2H Prey Pooling	32296183
种属内	KIZ	Q2M2Z5	TFIP11	Homo sapiens	Q9UBB9	Validated Y2H	32296183
种属内	KIZ	Q2M2Z5	TACC3	Homo sapiens	Q9Y6A5	Validated Y2H	25416956
种属内	KIZ	Q2M2Z5	TACC3	Homo sapiens	Q9Y6A5	Validated Y2H	32296183
种属内	KIZ	Q2M2Z5	TACC3	Homo sapiens	Q9Y6A5	Y2H Array	25416956
种属内	KIZ	Q2M2Z5	TACC3	Homo sapiens	Q9Y6A5	Y2H Array	32296183
种属内	KIZ	Q2M2Z5	TACC3	Homo sapiens	Q9Y6A5	Y2H Prey Pooling	25416956
种属内	KIZ	Q2M2Z5	TACC3	Homo sapiens	Q9Y6A5	Y2H Prey Pooling	32296183
种属内	KIZ	Q2M2Z5	FGFR3	Homo sapiens	P22607	Validated Y2H	32814053
种属内	KIZ	Q2M2Z5	FGFR3	Homo sapiens	P22607	Y2H Pooling	32814053
种属内	KIZ	Q2M2Z5	FGFR3	Homo sapiens	P22607	Y2H Array	32814053
种属内	KIZ	Q2M2Z5	HRAS	Homo sapiens	P01112	Y2H Pooling	32814053
种属内	KIZ	Q2M2Z5	HRAS	Homo sapiens	P01112	Validated Y2H	32814053
种属内	KIZ	Q2M2Z5	HRAS	Homo sapiens	P01112	Y2H Array	32814053
种属内	KIZ	Q2M2Z5	CEP72	Homo sapiens	Q9P209	Anti Bait CoIP	19536135
种属内	KIZ	Q2M2Z5	CEP72	Homo sapiens	Q9P209	IF	19536135
种属内	KIZ	Q2M2Z5	MEOX2	Homo sapiens	P50222	Validated Y2H	25416956
种属内	KIZ	Q2M2Z5	MEOX2	Homo sapiens	P50222	Y2H Prey Pooling	25416956

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Retinitis Pigmentosa 69

RP69	Retinitis Pigmentosa, Type 69

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

Fundus Dystrophy

Retinal Dystrophy	Retinal Dystrophies
Dystrophy, Retinal

Cone-Rod Dystrophy 2

Cone-Rod Dystrophy	CORD2
Cone-Rod Retinal Dystrophy	Rcrd2
Cone-Rod Retinal Dystrophy 2	Crd2
Cord	Crd
Retinal Cone-Rod Dystrophy	Cone-Rod Retinal Dystrophy-2
Retinal Cone-Rod Dystrophy 2	Tapetoretinal Degeneration
Cone-Rod Degeneration	Cone Rod Dystrophy
Dystrophy, Cone-Rod	Dystrophy, Cone-Rod, Type 2
Retinitis Pigmentosa	Retinitis Pigmentosa 2
Progressive Cone-Rod Dystrophy

Pica Disease

Pica

Preretinal Fibrosis

Cellophane Maculopathy	Macular Puckering Of Retina
Macular Retinal Puckering	Epiretinal Membrane

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS07323	KIZ Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	KIZ	MGD	MGI:2684960
Rattus norvegicus	KIZ	RGD	RGD:1307071
Canis familiaris	KIZ	VGNC	VGNC:42424
Macaca mulatta	KIZ	VGNC	VGNC:73838
Bos taurus	KIZ	VGNC	VGNC:30620
Felis catus	KIZ	VGNC	VGNC:63125

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2025 MedChemExpress. All Rights Reserved.

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

KIZ - kizuna centrosomal protein Gene

关于 KIZ

功能概要

KIZ 基因产物(7)

KIZ 蛋白互作信息

关联疾病

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

KIZ - kizuna centrosomal protein Gene

关于 KIZ

功能概要

KIZ 基因产物(7)

KIZ 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z