1. Gene
  2. Hgs - hepatocyte growth factor-regulated tyrosine kinase substrate Gene

Hgs - hepatocyte growth factor-regulated tyrosine kinase substrate Gene

种属: Rattus norvegicus

同用名: Hrs

基因 ID: 56084 | 基因类型: protein coding

关于 Hgs

功能概要

Predicted to enable several functions, including identical protein binding activity; ubiquitin-dependent protein binding activity; and ubiquitin-like protein Ligase binding activity. Involved in endosome to lysosome transport. Located in cytosol; membrane; and secretory granule. Orthologous to human HGS (hepatocyte growth factor-regulated tyrosine kinase substrate). [provided by Alliance of Genome Resources, Apr 2022]

Hgs 基因产物(3)

mRNA Protein Name
NM_001399619.1 NP_001386548.1 hepatocyte growth factor-regulated tyrosine kinase substrate isoform 2
NM_001399620.1 NP_001386549.1 hepatocyte growth factor-regulated tyrosine kinase substrate isoform 3
NM_019387.3 NP_062260.2 hepatocyte growth factor-regulated tyrosine kinase substrate isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10825299 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in endosome to lysosome transport IMP
IMP: 通过突变表型推断
19808888 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in secretory granule IDA
IDA: 通过直接分析推断
10825299 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

hepatocyte growth factor-regulated tyrosine kinase substrate

HGF-regulated tyrosine kinase substrate

SNAP-25-interacting protein Hrs-2

Hgs 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Hgs Q9JJ50 Hap1 Rattus norvegicus P54256
Anti Bait CoIP
12021262
种属内
Hgs Q9JJ50 Hap1 Rattus norvegicus P54256
Pull Down
12021262
种属内
Hgs Q9JJ50 Hap1 Rattus norvegicus P54256
Y2H
12021262
种属内
Hgs Q9JJ50 Hap1 Rattus norvegicus P54256-2
Density Sedimentation
12021262
种属内
Hgs Q9JJ50 Hap1 Rattus norvegicus P54256-2
Confocal
12021262
种属内
Hgs Q9JJ50 Hap1 Rattus norvegicus P54256-2
Pull Down
12021262
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hgs NCBI NCBI:9146