2. Gene
  3. Fzr1 - fizzy and cell division cycle 20 related 1 Gene

Fzr1 - fizzy and cell division cycle 20 related 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: FZR; Fyr; Cdh1; FZR2; HCDH; HCDH1

基因 ID: 56371 | 基因类型: protein coding

关于 Fzr1

功能概要

Predicted to enable anaphase-promoting complex binding activity and ubiquitin Ligase activator activity. Involved in negative regulation of cell aging and positive regulation of cell population proliferation. Acts upstream of or within lens fiber cell differentiation; proteolysis involved in cellular protein catabolic process; and regulation of meiotic nuclear division. Predicted to be located in nuclear membrane and nucleoplasm. Predicted to be part of anaphase-promoting complex. Is expressed in several structures, including central nervous system; liver; oocyte; sensory organ; and skeleton. Orthologous to human FZR1 (fizzy and cell division cycle 20 related 1). [provided by Alliance of Genome Resources, Apr 2022]

Fzr1 基因产物(1)

mRNA Protein Name
NM_019757.1 NP_062731.1 fizzy-related protein homolog
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17215516 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within lens fiber cell differentiation IMP
IMP: 通过突变表型推断
17215516 MGI
involved in negative regulation of cellular senescence IMP
IMP: 通过突变表型推断
21241890 MGI
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
21241890 MGI
acts upstream of or within proteolysis involved in protein catabolic process IMP
IMP: 通过突变表型推断
23541922 MGI
acts upstream of or within regulation of meiotic nuclear division IDA
IDA: 通过直接分析推断
17190794 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

fizzy-related protein homolog

cdh1/Hct1 homolog

cell division cycle 20 related 1

fizzy/cell division cycle 20 related 1

Fzr1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Fzr1 Q9R1K5 Sirt2 Mus musculus Q8VDQ8
Anti Bait CoIP
22014574
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05186 FZR1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Fzr1 NCBI NCBI:51343
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