AKIP1 - A-kinase interacting protein 1 Gene

中文名称：A-激酶相互作用蛋白 1

种属: Homo sapiens

同用名: BCA3; C11orf17

基因 ID: 56672 | 基因类型: protein coding

关于 AKIP1

Cytogenetic location: 11p15.4 Genomic coordinates (GRCh38): 11:8,911,189-8,920,079 (from NCBI)

This gene has 11 transcripts (splice variants) and 170 orthologues. Ubiquitous expression in thyroid (RPKM 4.3), adrenal (RPKM 4.1) and 25 other tissues.

功能概要

该基因编码与蛋白激酶 A 催化亚基相互作用的核蛋白，并调节 cAMP 依赖性蛋白激酶信号通路对 NF-kappa-B 激活级联的影响。已经描述了该基因的可变剪接转录物变体。[RefSeq 提供，2011 年 10 月]

This gene encodes a nuclear protein that interacts with protein kinase A catalytic subunit, and regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]

AKIP1 基因产物(4)

mRNA	Protein	Name
NM_001206646.2	NP_001193575.1	A-kinase-interacting protein 1 isoform b
NM_001206647.2	NP_001193576.1	A-kinase-interacting protein 1 isoform c
NM_001206648.2	NP_001193577.1	A-kinase-interacting protein 1 isoform d
NM_020642.4	NP_065693.2	A-kinase-interacting protein 1 isoform a

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	15630084	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

A-kinase-interacting protein 1

A kinase (PRKA) interacting protein 1

AKIP1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	AKIP1	Q9NQ31	q9y649_human	Homo sapiens	Q9Y649	Validated Y2H	32814053
Intra	AKIP1	Q9NQ31	q9y649_human	Homo sapiens	Q9Y649	Y2H Array	32814053
Intra	AKIP1	Q9NQ31	q9y649_human	Homo sapiens	Q9Y649	Y2H Pooling	32814053
Intra	AKIP1	Q9NQ31	FGFR3	Homo sapiens	P22607	Validated Y2H	32814053
Intra	AKIP1	Q9NQ31	FGFR3	Homo sapiens	P22607	Y2H Pooling	32814053
Intra	AKIP1	Q9NQ31	FGFR3	Homo sapiens	P22607	Y2H Array	32814053
Intra	AKIP1	Q9NQ31	GSN	Homo sapiens	P06396	Y2H Array	32814053
Intra	AKIP1	Q9NQ31	GSN	Homo sapiens	P06396	Validated Y2H	32814053
Intra	AKIP1	Q9NQ31	GSN	Homo sapiens	P06396	Y2H Pooling	32814053
Intra	AKIP1	Q9NQ31	PRKACA	Homo sapiens	P17612	Y2H	15630084
Intra	AKIP1	Q9NQ31	PRKACA	Homo sapiens	P17612	Pull Down	15630084
Intra	AKIP1	Q9NQ31	PRKACA	Homo sapiens	P17612	CoIP	15630084

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS00526	AKIP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	AKIP1	RGD	RGD:1306959
Macaca mulatta	AKIP1	VGNC	VGNC:69600
Canis familiaris	AKIP1	VGNC	VGNC:37764
Bos taurus	AKIP1	VGNC	VGNC:25792
Felis catus	AKIP1	VGNC	VGNC:59720
Mus musculus	AKIP1	MGD	MGI:3041226

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

AKIP1 - A-kinase interacting protein 1 Gene

关于 AKIP1

功能概要

AKIP1 基因产物(4)

AKIP1 蛋白互作信息

关联疾病

直系同源

热门区域

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AKIP1 - A-kinase interacting protein 1 Gene

关于 AKIP1

功能概要

AKIP1 基因产物(4)

AKIP1 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z