2. Gene
  3. SH3GLB2 - SH3 domain containing GRB2 like, endophilin B2 Gene

SH3GLB2 - SH3 domain containing GRB2 like, endophilin B2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 SH3 结构域的 GRB2 样、嗜内源性蛋白 B2

种属: Homo sapiens

同用名: RRIG1; PP6569; PP9455

基因 ID: 56904 | 基因类型: protein coding

关于 SH3GLB2

Cytogenetic location: 9q34.11 Genomic coordinates (GRCh38): 9:129,007,036-129,028,331 (from NCBI)

This gene has 12 transcripts (splice variants), 274 orthologues and 12 paralogues. Ubiquitous expression in skin (RPKM 45.1), prostate (RPKM 29.7) and 25 other tissues.

功能概要

实现相同的蛋白质结合活性。位于细胞质和核质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

SH3GLB2 基因产物(6)

mRNA Protein Name
NM_001287045.2 NP_001273974.1 endophilin-B2 isoform a
NM_001287046.2 NP_001273975.1 endophilin-B2 isoform b
NM_001369913.1 NP_001356842.1 endophilin-B2 isoform c
NM_001369914.1 NP_001356843.1 endophilin-B2 isoform d
NM_001369915.1 NP_001356844.1 endophilin-B2 isoform e
NM_020145.4 NP_064530.1 endophilin-B2 isoform b

SH3GLB2 蛋白结构

BAR

BAR: BAR domain (16 - 279)

SH3_9

SH3_9: Variant SH3 domain (342 - 392)

  • 0
  • 100
  • 200
  • 300
  • 395 a.a.
蛋白主名 其他名称

endophilin-B2

SH3 domain-containing GRB2-like protein B2

SH3GLB2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SH3GLB2 Q9NR46 SH3GLB1 Homo sapiens Q9Y371
Validated Y2H
32296183
Intra SH3GLB2 Q9NR46 SH3GLB1 Homo sapiens Q9Y371
MAPPIT
25416956
Intra SH3GLB2 Q9NR46 SH3GLB1 Homo sapiens Q9Y371
Anti Tag CoIP
35271311
Intra SH3GLB2 Q9NR46 SH3GLB1 Homo sapiens Q9Y371
Anti Tag CoIP
20562859
Intra SH3GLB2 Q9NR46 SH3GLB1 Homo sapiens Q9Y371
BFG-2H
27107012
Intra SH3GLB2 Q9NR46 SH3GLB1 Homo sapiens Q9Y371
Anti Tag CoIP
33961781
Intra SH3GLB2 Q9NR46 TBC1D7 Homo sapiens Q9P0N9
Validated Y2H
32296183
Intra SH3GLB2 Q9NR46 NXF1 Homo sapiens Q9UBU9
Validated Y2H
32296183
Intra SH3GLB2 Q9NR46 HTRA2 Homo sapiens O43464
Validated Y2H
32814053
Intra SH3GLB2 Q9NR46 HTRA2 Homo sapiens O43464
Y2H Array
32814053
Intra SH3GLB2 Q9NR46 HTRA2 Homo sapiens O43464
Y2H Pooling
32814053
Intra SH3GLB2 Q9NR46 MAGEA1 Homo sapiens P43355
BFG-2H
27107012
Intra SH3GLB2 Q9NR46 PICK1 Homo sapiens Q9NRD5
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Epidermolysis Bullosa Simplex 5b, With Muscular Dystrophy

Epidermolysis Bullosa Simplex With Muscular Dystrophy

Md-Ebs

Epidermolysis Bullosa Simplex And Limb-Girdle Muscular Dystrophy

EBS5B

Ebsmd

Mdebs

Limb-Girdle Muscular Dystrophy With Epidermolysis Bullosa Simplex

Ebs-Md

Epidermolysa Bullosa Simplex And Limb Girdle Muscular Dystrophy

Epidermolysa Bullosa Simplex With Muscular Dystrophy

Epidermolysis Bullosa Simplex - Limb Girdle Muscular Dystrophy

Ebs With Muscular Dystrophy

Muscular Dystrophy With Epidermolysis Bullosa Simplex

Epidermolysa Bullosa Simplex, With Muscular Dystrophy
Epidermolysis Bullosa, Junctional 5b, With Pyloric Atresia

Junctional Epidermolysis Bullosa With Pyloric Atresia

Carmi Syndrome

Epidermolysis Bullosa, Junctional, With Pyloric Atresia

Jeb-Pa

JEB5B

Epidermolysis Bullosa Junctionalis With Pyloric Atresia

Aplasia Cutis Congenita With Gastrointestinal Atresia

Epidermolysis Bullosa, Junctional, With Pyloric Atresia And Aplasia Cutis Congenita

Eb-Pa-Acc

Junctional Epidermolysis Bullosa-Pyloric Atresia Syndrome

Jeb With Pyloric Atresia

Epidermolysis Bullosa Letalis, With Pyloric Atresia

Pa-Jeb

Epidermolysis Bullosa With Pyloric Atresia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12840 SH3GLB2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris SH3GLB2 VGNC VGNC:46128
Rattus norvegicus SH3GLB2 RGD RGD:1305886
Macaca mulatta SH3GLB2 VGNC VGNC:77207
Mus musculus SH3GLB2 MGD MGI:2385131
Felis catus SH3GLB2 VGNC VGNC:65110
Bos taurus SH3GLB2 VGNC VGNC:34576
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