1. Gene
  2. WDR18 - WD repeat domain 18 Gene

WDR18 - WD repeat domain 18 Gene

中文名称:WD 重复域 18

种属: Homo sapiens

同用名: Ipi3; R32184_1

基因 ID: 57418 | 基因类型: protein coding

关于 WDR18

This gene has 11 transcripts (splice variants) and 194 orthologues. Ubiquitous expression in kidney (RPKM 9.8), colon (RPKM 5.8) and 25 other tissues.

功能概要

该基因编码 WD 重复蛋白家族的一个成员。 WD 重复是大约 40 个氨基酸的最小保守区域,通常由 gly-his 和 trp-asp (GH-WD) 括起来,这可能有助于异源三聚体或多蛋白复合物的形成。该家族的成员参与多种细胞过程,包括细胞周期进程、信号转导、细胞凋亡和基因调控。[RefSeq 提供,2008 年 7 月]

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 Amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, Apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]

WDR18 基因产物(3)

mRNA Protein Name
NM_001372085.1 NP_001359014.1 WD repeat-containing protein 18 isoform 1
NM_001372086.1 NP_001359015.1 WD repeat-containing protein 18 isoform 2
NM_024100.4 NP_077005.2 WD repeat-containing protein 18 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21326211 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

WDR18 蛋白结构

WD40

WD40: WD domain, G-beta repeat (102 - 139)

  • 0
  • 100
  • 189 a.a.
蛋白主名 其他名称

WD repeat-containing protein 18

Involved in Processing ITS2 3 homolog

WDR18 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra WDR18 Q9BV38 TEX10 Homo sapiens Q9NXF1
Anti Tag CoIP
33961781
Intra WDR18 Q9BV38 TEX10 Homo sapiens Q9NXF1
Anti Tag CoIP
28514442
Intra WDR18 Q9BV38 SENP3 Homo sapiens Q9H4L4
Anti Tag CoIP
21326211
Intra WDR18 Q9BV38 SENP3 Homo sapiens Q9H4L4
Anti Tag CoIP
33961781
Intra WDR18 Q9BV38 SENP3 Homo sapiens Q9H4L4
Anti Tag CoIP
28514442
Intra WDR18 Q9BV38 PELP1 Homo sapiens Q8IZL8
Anti Tag CoIP
33961781
Intra WDR18 Q9BV38 PELP1 Homo sapiens Q8IZL8
Anti Tag CoIP
28514442
Intra WDR18 Q9BV38 PELP1 Homo sapiens Q8IZL8
Anti Bait CoIP
36351913
Intra WDR18 Q9BV38 PELP1 Homo sapiens Q8IZL8
Anti Tag CoIP
21326211
Intra WDR18 Q9BV38 PELP1 Homo sapiens Q8IZL8
Crosslink
30021884
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Bos taurus WDR18 VGNC VGNC:36885
Canis familiaris WDR18 VGNC VGNC:48354
Mus musculus WDR18 MGD MGI:2158400
Rattus norvegicus WDR18 RGD RGD:1310646
Macaca mulatta WDR18 VGNC VGNC:79103
Felis catus WDR18 VGNC VGNC:67018