2. Gene
  3. SFMBT2 - Scm like with four mbt domains 2 Gene

SFMBT2 - Scm like with four mbt domains 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：SCM 就样有四个 mbt 域 2

种属: Homo sapiens

基因 ID: 57713 | 基因类型: protein coding

关于 SFMBT2

Cytogenetic location: 10p14 Genomic coordinates (GRCh38): 10:7,158,624-7,411,490 (from NCBI)

This gene has 11 transcripts (splice variants), 217 orthologues and 18 paralogues. Ubiquitous expression in thyroid (RPKM 4.8), ovary (RPKM 4.5) and 24 other tissues.

功能概要

启用组蛋白结合活动。参与基因表达的负调控。位于侵略;胞质溶胶；和核斑点。 [由基因组资源联盟提供，2022 年 4 月]

Enables histone binding activity. Involved in negative regulation of gene expression. Located in aggresome; cytosol; and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

SFMBT2 基因产物(5)

mRNA Protein Name
NM_001018039.1 NP_001018049.1 scm-like with four MBT domains protein 2 isoform 1
NM_001029880.3 NP_001025051.1 scm-like with four MBT domains protein 2 isoform 1
NM_001387889.1 NP_001374818.1 scm-like with four MBT domains protein 2 isoform 1
NM_001387890.1 NP_001374819.1 scm-like with four MBT domains protein 2 isoform 2
NM_001387891.1 NP_001374820.1 scm-like with four MBT domains protein 2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone binding IDA
IDA: 通过直接分析推断
23385818 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
23385818 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of gene expression IDA
IDA: 通过直接分析推断
23385818 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
23385818 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SFMBT2 蛋白结构

MBT

MBT: mbt repeat (78 - 150)

MBT

MBT: mbt repeat (193 - 258)

MBT

MBT: mbt repeat (304 - 379)

MBT

MBT: mbt repeat (412 - 483)

SLED

SLED: SLED domain (528 - 644)

SAM_1

SAM_1: SAM domain (Sterile alpha motif) (823 - 885)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 894 a.a.
蛋白主名 其他名称

scm-like with four MBT domains protein 2

Scm-related gene containing four mbt domains 2

SFMBT2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SFMBT2 Q5VUG0 SIAH1 Homo sapiens Q8IUQ4-2
Validated Y2H
32296183
Intra SFMBT2 Q5VUG0 SIAH1 Homo sapiens Q8IUQ4-2
Y2H Prey Pooling
32296183
Intra SFMBT2 Q5VUG0 SIAH1 Homo sapiens Q8IUQ4-2
Y2H Array
32296183
Intra SFMBT2 Q5VUG0 L3MBTL3 Homo sapiens Q96JM7-2
Y2H Array
32296183
Intra SFMBT2 Q5VUG0 L3MBTL3 Homo sapiens Q96JM7-2
Validated Y2H
32296183
Intra SFMBT2 Q5VUG0 L3MBTL3 Homo sapiens Q96JM7-2
Y2H Prey Pooling
32296183
Intra SFMBT2 Q5VUG0 SCML1 Homo sapiens Q9UN30-2
Validated Y2H
32296183
Intra SFMBT2 Q5VUG0 SCML1 Homo sapiens Q9UN30-2
Y2H Array
32296183
Intra SFMBT2 Q5VUG0 SCML1 Homo sapiens Q9UN30-2
Y2H Prey Pooling
32296183
Intra SFMBT2 Q5VUG0 UBE2O Homo sapiens Q9C0C9
Validated Y2H
32296183
Intra SFMBT2 Q5VUG0 UBE2O Homo sapiens Q9C0C9
Y2H Prey Pooling
32296183
Intra SFMBT2 Q5VUG0 UBE2O Homo sapiens Q9C0C9
Y2H Array
32296183
Intra SFMBT2 Q5VUG0 SCML2 Homo sapiens Q9UQR0
Y2H Array
32296183
Intra SFMBT2 Q5VUG0 SCML2 Homo sapiens Q9UQR0
Validated Y2H
32296183
Intra SFMBT2 Q5VUG0 SCML2 Homo sapiens Q9UQR0
Y2H Prey Pooling
32296183
Intra SFMBT2 Q5VUG0 SLF2 Homo sapiens Q8IX21
Y2H Array
32296183
Intra SFMBT2 Q5VUG0 SLF2 Homo sapiens Q8IX21
Y2H Prey Pooling
32296183
Intra SFMBT2 Q5VUG0 SLF2 Homo sapiens Q8IX21
Validated Y2H
32296183
Intra SFMBT2 Q5VUG0 SCMH1 Homo sapiens Q96GD3
Validated Y2H
32296183
Intra SFMBT2 Q5VUG0 PHC1 Homo sapiens P78364
Y2H Array
32296183
Intra SFMBT2 Q5VUG0 PHC1 Homo sapiens P78364
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12768 SFMBT2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus SFMBT2 VGNC VGNC:65062
Macaca mulatta SFMBT2 VGNC VGNC:77280
Mus musculus SFMBT2 MGD MGI:2447794
Bos taurus SFMBT2 VGNC VGNC:34516
Canis familiaris SFMBT2 VGNC VGNC:46077
Rattus norvegicus SFMBT2 RGD RGD:1305027
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z