2. Gene
  3. SCMH1 - Scm polycomb group protein homolog 1 Gene

SCMH1 - Scm polycomb group protein homolog 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：Scm 多梳组蛋白同系物 1

种属: Homo sapiens

同用名: Scml3

基因 ID: 22955 | 基因类型: protein coding

关于 SCMH1

Cytogenetic location: 1p34.2 Genomic coordinates (GRCh38): 1:41,027,202-41,242,306 (from NCBI)

This gene has 15 transcripts (splice variants), 222 orthologues and 18 paralogues. Ubiquitous expression in testis (RPKM 14.6), ovary (RPKM 12.4) and 25 other tissues.

功能概要

预测启用染色质结合活性和组蛋白结合活性。预测参与转录的负调控，DNA 模板化。预测作用于前/后模式规范的上游或之内；染色质重塑；和精子发生。预测位于核质中。预计活跃于核心。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to act upstream of or within anterior/posterior pattern specification; chromatin remodeling; and spermatogenesis. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

SCMH1 基因产物(21)

mRNA Protein Name
NM_001031694.3 NP_001026864.1 polycomb protein SCMH1 isoform a
NM_001172218.2 NP_001165689.1 polycomb protein SCMH1 isoform c
NM_001172219.2 NP_001165690.1 polycomb protein SCMH1 isoform d
NM_001172220.2 NP_001165691.1 polycomb protein SCMH1 isoform c
NM_001172221.3 NP_001165692.1 polycomb protein SCMH1 isoform e
NM_001172222.3 NP_001165693.1 polycomb protein SCMH1 isoform f
NM_001350667.2 NP_001337596.1 polycomb protein SCMH1 isoform g
NM_001350668.2 NP_001337597.1 polycomb protein SCMH1 isoform h
NM_001394299.1 NP_001381228.1 polycomb protein SCMH1 isoform i
NM_001394300.1 NP_001381229.1 polycomb protein SCMH1 isoform a
NM_001394301.1 NP_001381230.1 polycomb protein SCMH1 isoform a
NM_001394302.1 NP_001381231.1 polycomb protein SCMH1 isoform a
NM_001394303.1 NP_001381232.1 polycomb protein SCMH1 isoform e
NM_001394304.1 NP_001381233.1 polycomb protein SCMH1 isoform i
NM_001394305.1 NP_001381234.1 polycomb protein SCMH1 isoform i
NM_001394306.1 NP_001381235.1 polycomb protein SCMH1 isoform i
NM_001394307.1 NP_001381236.1 polycomb protein SCMH1 isoform j
NM_001394308.1 NP_001381237.1 polycomb protein SCMH1 isoform k
NM_001394309.1 NP_001381238.1 polycomb protein SCMH1 isoform l
NM_001394311.1 NP_001381240.1 polycomb protein SCMH1 isoform m
NM_012236.4 NP_036368.1 polycomb protein SCMH1 isoform b
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SCMH1 蛋白结构

MBT

MBT: mbt repeat (62 - 132)

MBT

MBT: mbt repeat (171 - 236)

SLED

SLED: SLED domain (356 - 469)

SAM_1

SAM_1: SAM domain (Sterile alpha motif) (591 - 656)

  • 0
  • 200
  • 400
  • 600
  • 660 a.a.
蛋白主名 其他名称

polycomb protein SCMH1

sex comb on midleg homolog 1

SCMH1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SCMH1 Q96GD3 UBQLN1 Homo sapiens Q9UMX0-2
Validated Y2H
25416956
Intra SCMH1 Q96GD3 UBQLN1 Homo sapiens Q9UMX0-2
Y2H Prey Pooling
25416956
Intra SCMH1 Q96GD3 SFMBT2 Homo sapiens Q5VUG0
Y2H Array
32296183
Intra SCMH1 Q96GD3 SFMBT2 Homo sapiens Q5VUG0
Y2H Prey Pooling
32296183
Intra SCMH1 Q96GD3 UBQLN1 Homo sapiens Q9UMX0
Y2H Prey Pooling
25416956
Intra SCMH1 Q96GD3 HPCAL4 Homo sapiens Q9UM19
Validated Y2H
32296183
Intra SCMH1 Q96GD3 HPCAL4 Homo sapiens Q9UM19
Y2H Prey Pooling
32296183
Intra SCMH1 Q96GD3 HPCAL4 Homo sapiens Q9UM19
Y2H Array
32296183
Intra SCMH1 Q96GD3 SFMBT1 Homo sapiens Q9UHJ3
Y2H Prey Pooling
32296183
Intra SCMH1 Q96GD3 SFMBT1 Homo sapiens Q9UHJ3
Validated Y2H
32296183
Intra SCMH1 Q96GD3 SFMBT1 Homo sapiens Q9UHJ3
Y2H Array
32296183
Intra SCMH1 Q96GD3 MAGEA12 Homo sapiens P43365
Y2H Array
25416956
Intra SCMH1 Q96GD3 MAGEA12 Homo sapiens P43365
Y2H Prey Pooling
25416956
Intra SCMH1 Q96GD3 MAGEA12 Homo sapiens P43365
Validated Y2H
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12515 SCMH1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus SCMH1 VGNC VGNC:64916
Canis familiaris SCMH1 VGNC VGNC:45910
Mus musculus SCMH1 MGD MGI:1352762
Bos taurus SCMH1 VGNC VGNC:34340
Macaca mulatta SCMH1 VGNC VGNC:77051
Rattus norvegicus SCMH1 RGD RGD:1305788
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