2. Gene
  3. Sh3kbp1 - SH3-domain kinase binding protein 1 Gene

Sh3kbp1 - SH3-domain kinase binding protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Ruk; IN85; Seta; Cin85; 1200007H22Rik; 1700125L08Rik; 5830464D22Rik

基因 ID: 58194 | 基因类型: protein coding

关于 Sh3kbp1

功能概要

Predicted to enable ubiquitin protein Ligase binding activity. Predicted to be involved in several processes, including actin filament organization; positive regulation of B cell activation; and regulation of cell shape. Predicted to act upstream of or within apoptotic process and endocytosis. Located in cell-cell junction and endocytic vesicle. Is expressed in embryo. Human ortholog(s) of this gene implicated in immunodeficiency 61. Orthologous to human SH3KBP1 (SH3 domain containing kinase binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Sh3kbp1 基因产物(6)

mRNA Protein Name
NM_001135727.2 NP_001129199.1 SH3 domain-containing kinase-binding protein 1 isoform 1
NM_001135728.2 NP_001129200.1 SH3 domain-containing kinase-binding protein 1 isoform 3
NM_001290661.1 NP_001277590.1 SH3 domain-containing kinase-binding protein 1 isoform 4
NM_001290664.1 NP_001277593.1 SH3 domain-containing kinase-binding protein 1 isoform 4
NM_001374701.1 NP_001361630.1 SH3 domain-containing kinase-binding protein 1 isoform 5
NM_021389.6 NP_067364.2 SH3 domain-containing kinase-binding protein 1 isoform 2
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11152963 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell-cell junction IDA
IDA: 通过直接分析推断
23793062 MGI
located in endocytic vesicle IDA
IDA: 通过直接分析推断
21830225 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

SH3 domain-containing kinase-binding protein 1

Ruk(deltaA) protein

Ruk(h) protein

Ruk(l) protein

Ruk(m1) protein

Ruk(m3) protein

Ruk(t) protein

Ruk(xl) protein

SH3-containing, expressed in tumorigenic astrocytes

regulator of ubiquitous kinase

Sh3kbp1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Sh3kbp1 Q8R550 Dlg4 Mus musculus Q62108
Anti Bait CoIP
20551902
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12841 SH3KBP1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sh3kbp1 NCBI NCBI:30011
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