2. Gene
  3. MYL7 - myosin light chain 7 Gene

MYL7 - myosin light chain 7 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：肌球蛋白轻链 7

种属: Homo sapiens

同用名: MYL2A; MYLC2A

基因 ID: 58498 | 基因类型: protein coding

关于 MYL7

Cytogenetic location: 7p13 Genomic coordinates (GRCh38): 7:44,138,864-44,141,332 (from NCBI)

This gene has 10 transcripts (splice variants), 186 orthologues and 7 paralogues. Restricted expression toward heart (RPKM 2260.5).

功能概要

预测可启用钙离子结合活性。位于 A 带。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable calcium ion binding activity. Located in A band. [provided by Alliance of Genome Resources, Apr 2022]

MYL7 基因产物(1)

mRNA Protein Name
NM_021223.3 NP_067046.1 myosin regulatory light chain 2, atrial isoform
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in A band IDA
IDA: 通过直接分析推断
15621049 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MYL7 蛋白结构

EF-hand_7

EF-hand_7: EF-hand domain pair (38 - 130)

  • 0
  • 100
  • 175 a.a.
蛋白主名 其他名称

myosin regulatory light chain 2, atrial isoform

MLC-2a

MYL7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra MYL7 Q01449 PSORS1C2 Homo sapiens Q9UIG4
Validated Y2H
32296183
Intra MYL7 Q01449 MCCD1 Homo sapiens P59942
Y2H Prey Pooling
32296183
Intra MYL7 Q01449 MCCD1 Homo sapiens P59942
Y2H Array
32296183
Intra MYL7 Q01449 POU6F2 Homo sapiens P78424
Y2H Prey Pooling
32296183
Intra MYL7 Q01449 POU6F2 Homo sapiens P78424
Y2H Array
32296183
Intra MYL7 Q01449 MEOX2 Homo sapiens Q6FHY5
Validated Y2H
32296183
Intra MYL7 Q01449 MEOX2 Homo sapiens Q6FHY5
Y2H Prey Pooling
32296183
Intra MYL7 Q01449 MEOX2 Homo sapiens Q6FHY5
Y2H Array
32296183
Intra MYL7 Q01449 PPM1B Homo sapiens O75688-3
Y2H Prey Pooling
32296183
Intra MYL7 Q01449 PPM1B Homo sapiens O75688-3
Y2H Array
32296183
Intra MYL7 Q01449 TOX4 Homo sapiens O94842
Y2H Prey Pooling
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Cardiomyopathy, Familial Hypertrophic, 1

Asymmetric Septal Hypertrophy

Familial Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy 1

CMH1

Hypertrophic Cardiomyopathy 19

CMH

Ventricular Hypertrophy, Hereditary

Ash

Hypertrophic Subaortic Stenosis, Idiopathic

Cardiomyopathy, Familial Hypertrophic

Cardiomyopathy, Hypertrophic, 1, Digenic

Cardiomyopathy, Familial Hypertrophic 1

Hcm

Hereditary Ventricular Hypertrophy

Idiopathic Hypertrophic Subaortic Stenosis

Hypertrophic Cardiomyopathy

Cardiomyopathy, Hypertrophic, Familial

Cardiomyopathy, Hypertrophic, 1

Familial Asymmetric Septal Hypertrophy

Heritable Hypertrophic Cardiomyopathy

Fhc

Cardiomyopathy, Hypertrophic, Familial, Type 1
Hypertrophic Cardiomyopathy

Hypertrophic Obstructive Cardiomyopathy

Cardiomyopathy, Hypertrophic

Cardiomyopathy Hypertrophic Obstructive

Cardiomyopathy, Hypertrophic, Familial

Idiopathic Myocardial Hypertrophy

Idiopathic Hypertrophic Cardiomyopathy

Obstructive Idiopathic Hypertrophic Cardiomyopathy

Obstructive Cardiomyopathy

Idiopathic Hypertrophic Subaortic Stenosis

Muscular Subaortic Stenosis

Hypertrophic Obstructive Subaortic Stenosis
Familial Atrial Fibrillation

Atrial Fibrillation, Familial

Atfb

Atrial Fibrillation Autosomal Dominant

Autosomal Dominant Atrial Fibrillation

Auricular Fibrillation

Atrial Fibrillation

Atrial Fibrillation, Familial, 1
Left Ventricular Noncompaction

Noncompaction Cardiomyopathy

Left Ventricular Hypertrabeculation

Lvnc

Spongy Myocardium

Isolated Noncompaction Of The Ventricular Myocardium

Left Ventricular Myocardial Noncompaction Cardiomyopathy

Fetal Myocardium

Honeycomb Myocardium

Hypertrabeculation Syndrome

Left Ventricular Non-Compaction

Lvht

Non-Compaction Of The Left Ventricular Myocardium

Ventricular Noncompaction, Left

Non-Compaction Cardiomyopathy
Dilated Cardiomyopathy

Familial Dilated Cardiomyopathy

Primary Dilated Cardiomyopathy

Idiopathic Dilated Cardiomyopathy

Congestive Cardiomyopathy

Idiopathic Dilation Cardiomyopathy

Primary Familial Dilated Cardiomyopathy

Cardiomyopathy, Dilated

DCM

Cardiomyopathy, Familial Dilated

Dilated Cardiomyopathy, Familial

Hypokinetic Dilated Cardiomyopathy, Familial

Familial Idiopathic Cardiomyopathy

Fdc

Cardiomyopathy, Familial Idiopathic

Idiopathic Cardiomegaly

Dilated Congestive Cardiomyopathy

Chronic Dilated Cardiomyopathy

Ccm - [Congestive Cardiomyopathy]

Cocm - [Congestive Cardiomyopathy]

Dcm - [Dilated Cardiomyopathy]

Dilated-Hypokinetic Cardiomyopathy

Congestive Idiopathic Cardiomyopathy

Primary Idiopathic Dilated Cardiomyopathy
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08920 MYL7 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus MYL7 VGNC VGNC:31804
Felis catus MYL7 VGNC VGNC:63679
Mus musculus MYL7 MGD MGI:107495
Rattus norvegicus MYL7 RGD RGD:1308262
Macaca mulatta MYL7 VGNC VGNC:75002
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