1. Gene
  2. S1pr5 - sphingosine-1-phosphate receptor 5 Gene

S1pr5 - sphingosine-1-phosphate receptor 5 Gene

中文名称:1-磷酸鞘氨醇受体 5

种属: Rattus norvegicus

同用名: Edg8; Edg-8

基因 ID: 60399 | 基因类型: protein coding

关于 S1pr5

Primary_assembly 8: 19,786,663-19,791,795 reverse strand.mRatBN7.2:CM026981.1

This gene has 2 transcripts (splice variants), 236 orthologues, 18 paralogues and is associated with 2 phenotypes. Biased expression in Brain (RPKM 55.), Lung (RPKM 18.2) and 4 other tissues.

功能概要

该基因编码的蛋白可启动 G 蛋白偶联受体活性。参与调节神经元分化。是膜的组成部分。与人 S1PR5(1-磷酸鞘氨醇受体 5)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables G protein-coupled receptor activity. Involved in regulation of neuron differentiation. Is integral component of membrane. Orthologous to human S1PR5 (sphingosine-1-phosphate receptor 5). [provided by Alliance of Genome Resources, Apr 2022]

S1pr5 基因产物(1)

mRNA Protein Name
NM_021775.2 NP_068543.2 sphingosine 1-phosphate receptor 5
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor activity IDA
IDA: 通过直接分析推断
10799507 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of neuron differentiation IEP
IEP: 通过表达模式推断
12617946 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

S1pr5 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (36 - 317)

7tm_GPCRs

7tm_GPCRs: cd14964 (38 - 62)

7tm_GPCRs

7tm_GPCRs: cd14964 (71 - 92)

7tm_GPCRs

7tm_GPCRs: cd14964 (108 - 130)

7tm_GPCRs

7tm_GPCRs: cd14964 (152 - 168)

7tm_GPCRs

7tm_GPCRs: cd14964 (189 - 212)

7tm_GPCRs

7tm_GPCRs: cd14964 (250 - 272)

7tm_GPCRs

7tm_GPCRs: cd14964 (285 - 310)

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  • 400 a.a.
蛋白主名 其他名称

sphingosine 1-phosphate receptor 5

NRG-1

S1P receptor 5

S1P receptor Edg-8

S1P5

endothelial differentiation G-protein-coupled receptor 8

endothelial differentiation, sphingolipid G-protein-coupled receptor, 8

nerve growth factor-regulated G-protein-coupled receptor 1

sphingosine 1-phosphate receptor Edg-8

直系同源

种属 基因名 来源 基因 ID
Homo sapiens S1pr5 NCBI NCBI:53637