2. Gene
  3. FASTKD5 - FAST kinase domains 5 Gene

FASTKD5 - FAST kinase domains 5 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：FAST 激酶结构域 5

种属: Homo sapiens

同用名: dJ1187M17.5

基因 ID: 60493 | 基因类型: protein coding

关于 FASTKD5

Cytogenetic location: 20p13 Genomic coordinates (GRCh38): 20:3,146,519-3,159,865 (from NCBI)

This gene has 5 transcripts (splice variants), 147 orthologues and 5 paralogues. Ubiquitous expression in bone marrow (RPKM 15.0), adrenal (RPKM 8.0) and 25 other tissues.

功能概要

启用 rRNA 结合活动。参与线粒体 RNA 加工。位于线粒体类核和核糖核蛋白颗粒中。 [由基因组资源联盟提供，2022 年 4 月]

Enables rRNA binding activity. Involved in mitochondrial RNA processing. Located in mitochondrial nucleoid and ribonucleoprotein granule. [provided by Alliance of Genome Resources, Apr 2022]

FASTKD5 基因产物(1)

mRNA Protein Name
NM_021826.5 NP_068598.1 FAST kinase domain-containing protein 5, mitochondrial
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
enables rRNA binding IDA
IDA: 通过直接分析推断
25683715 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in mitochondrial RNA processing IMP
IMP: 通过突变表型推断
25683715 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial nucleoid IDA
IDA: 通过直接分析推断
25683715 GOA
located in mitochondrion IDA
IDA: 通过直接分析推断
20869947 GOA
located in ribonucleoprotein granule IDA
IDA: 通过直接分析推断
25683715 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

FASTKD5 蛋白结构

FAST_1

FAST_1: FAST kinase-like protein, subdomain 1 (430 - 500)

FAST_2

FAST_2: FAST kinase-like protein, subdomain 2 (511 - 602)

RAP

RAP: RAP domain (701 - 758)

  • 0
  • 200
  • 400
  • 600
  • 764 a.a.
蛋白主名 其他名称

FAST kinase domain-containing protein 5, mitochondrial

FASTKD5 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra FASTKD5 Q7L8L6 MID2 Homo sapiens Q9UJV3-2
Y2H Prey Pooling
32296183
Intra FASTKD5 Q7L8L6 MID2 Homo sapiens Q9UJV3-2
Validated Y2H
32296183
Intra FASTKD5 Q7L8L6 MID2 Homo sapiens Q9UJV3-2
Y2H Array
32296183
Intra FASTKD5 Q7L8L6 KCNH1 Homo sapiens O95259
Y2H Array
25416956
Intra FASTKD5 Q7L8L6 UBE2K Homo sapiens P61086
Y2H Array
32814053
Intra FASTKD5 Q7L8L6 UBE2K Homo sapiens P61086
Validated Y2H
32814053
Intra FASTKD5 Q7L8L6 UBE2K Homo sapiens P61086
Y2H Pooling
32814053
Intra FASTKD5 Q7L8L6 TRIM27 Homo sapiens P14373
Y2H Prey Pooling
32296183
Intra FASTKD5 Q7L8L6 TRIM27 Homo sapiens P14373
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Mitochondrial Dna Depletion Syndrome 4b

Mitochondrial Neurogastrointestinal Encephalopathy Syndrome

Mngie Syndrome

Thymidine Phosphorylase Deficiency

MTDPS4B

Mitochondrial Neurogastrointestinal Encephalopathy Disease

Mngie

Myoneurogastrointestinal Encephalopathy Syndrome

Ogimd

Oculogastrointestinal Muscular Dystrophy

Polip

Polyneuropathy, Ophthalmoplegia, Leukoencephalopathy, And Intestinal Pseudo-Obstruction

Mitochondrial Neurogastrointestinal Encephalopathy Syndrome, Polg-Related

Mngie, Polg-Related

Mepop

Mitochondrial Myopathy With Sensorimotor Polyneuropathy, Ophthalmoplegia, And Pseudo-Obstruction

Mngie Disease

Mitochondrial Dna Depletion Syndrome 4b Mngie Type

Mitochondrial Neurogastrointestinal Encephalopathy Syndrome Polg-Related

Mngie Polg-Related

Mitochondrial Dna Depletion Syndrome, Type 4b

Visceral Myopathy Familial External Ophthalmoplegia
Cardiomyopathy, Infantile Hypertrophic

Infantile Hypertrophic Cardiomyopathy

CMHI
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04759 FASTKD5 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus FASTKD5 VGNC VGNC:106736
Mus musculus FASTKD5 MGD MGI:2139469
Macaca mulatta FASTKD5 VGNC VGNC:84767
Rattus norvegicus FASTKD5 RGD RGD:1563839
Canis familiaris FASTKD5 VGNC VGNC:40741
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