2. Gene
  3. SCOC - short coiled-coil protein Gene

SCOC - short coiled-coil protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：短螺旋蛋白

种属: Homo sapiens

同用名: SCOCO; UNC-69; HRIHFB2072

基因 ID: 60592 | 基因类型: protein coding

关于 SCOC

This gene has 9 transcripts (splice variants) and 271 orthologues. Ubiquitous expression in brain (RPKM 55.6), thyroid (RPKM 34.6) and 25 other tissues.

功能概要

该基因编码一种短的卷曲螺旋结构域蛋白，定位于高尔基体。编码的蛋白质与 ADP-核糖基化因子样蛋白质相互作用。该基因的假基因存在于 1 号和 14 号染色体上。可变剪接导致多个转录变体。[RefSeq 提供，2009 年 4 月]

This gene encodes a short coiled-coiled domain-containing protein that localizes to the Golgi apparatus. The encoded protein interacts with ADP-ribosylation factor-like proteins. Pseudogenes of this gene are found on chromosomes 1 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

SCOC 基因产物(8)

mRNA Protein Name
NM_001153446.1 NP_001146918.1 short coiled-coil protein isoform 4
NM_001153484.2 NP_001146956.2 short coiled-coil protein isoform 1
NM_001153552.2 NP_001147024.2 short coiled-coil protein isoform 3
NM_001153585.1 NP_001147057.1 short coiled-coil protein isoform 4
NM_001153635.1 NP_001147107.1 short coiled-coil protein isoform 5
NM_001153663.1 NP_001147135.1 short coiled-coil protein isoform 2
NM_001153690.1 NP_001147162.1 short coiled-coil protein isoform 6
NM_032547.3 NP_115936.2 short coiled-coil protein isoform 4
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20195357 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of macroautophagy IDA
IDA: 通过直接分析推断
22354037 GOA
involved in regulation of protein complex stability IMP
IMP: 通过突变表型推断
22354037 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
colocalizes with endosome IDA
IDA: 通过直接分析推断
22354037 GOA
colocalizes with trans-Golgi network IDA
IDA: 通过直接分析推断
22354037 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SCOC 蛋白结构

DUF2205

DUF2205: Predicted coiled-coil protein (DUF2205) (79 - 159)

  • 0
  • 100
  • 159 a.a.
蛋白主名 其他名称

short coiled-coil protein

SCOC 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SCOC Q9UIL1 SCHIP1 Homo sapiens P0DPB3
TAP
20195357
Intra SCOC Q9UIL1 FEZ1 Homo sapiens Q99689
IF
22354037
Intra SCOC Q9UIL1 TCF4 Homo sapiens P15884
Validated Y2H
25416956
Intra SCOC Q9UIL1 TCF4 Homo sapiens P15884
Y2H Array
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Carotid Artery Dissection

Dissection Of Carotid Artery
Cannabis Dependence

Marijuana Abuse

Cannabinoid Addiction

Cannabinoid Dependence

Cannabis Addiction
Hallucinogen Dependence

Hallucinogen Addiction
Pyromania

Firesetting Behavior

Pathological Firesetting

Pathological Fire-Setting
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12558 SCOC Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SCOC RGD RGD:1311860
Bos taurus SCOC VGNC VGNC:34360
Mus musculus SCOC MGD MGI:1927654
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