2. Gene
  3. RPS23 - ribosomal protein S23 Gene

RPS23 - ribosomal protein S23 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：核糖体蛋白 S23

种属: Homo sapiens

同用名: S23; BTDD; uS12; MABAS; MCINS; PAMAS

基因 ID: 6228 | 基因类型: protein coding

关于 RPS23

Cytogenetic location: 5q14.2 Genomic coordinates (GRCh38): 5:82,273,320-82,278,354 (from NCBI)

This gene has 9 transcripts (splice variants), 182 orthologues, 1 paralogue and is associated with 2 phenotypes. Ubiquitous expression in ovary (RPKM 288.5), bone marrow (RPKM 141.7) and 25 other tissues.

功能概要

核糖体是催化蛋白质合成的细胞器，由一个小的 40S 亚基和一个大的 60S 亚基组成。这些亚基一起由 4 种 RNA 和大约 80 种结构不同的蛋白质组成。该基因编码的核糖体蛋白是 40S 亚基的一个组成部分。该蛋白属于核糖体蛋白的 S12P 家族。它位于细胞质中。该蛋白质与酿酒酵母核糖体蛋白 S28 具有显着的氨基酸相似性。作为典型的编码核糖体蛋白的基因，该基因有多个经过处理的假基因分散在基因组中。[RefSeq 提供，2008 年 7 月]

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S12P family of ribosomal proteins. It is located in the cytoplasm. The protein shares significant amino acid similarity with S. cerevisiae ribosomal protein S28. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

RPS23 基因产物(1)

mRNA Protein Name
NM_001025.5 NP_001016.1 40S ribosomal protein S23
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20434207 GOA
enables structural constituent of ribosome IDA
IDA: 通过直接分析推断
23636399 GOA
enables structural constituent of ribosome IMP
IMP: 通过突变表型推断
28257692 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cytoplasmic translation IDA
IDA: 通过直接分析推断
25957688 GOA
involved in maintenance of translational fidelity IMP
IMP: 通过突变表型推断
28257692 GOA
involved in ribosomal small subunit biogenesis IDA
IDA: 通过直接分析推断
34516797 GOA
involved in stress granule assembly IMP
IMP: 通过突变表型推断
28257692 GOA
involved in translation IMP
IMP: 通过突变表型推断
28257692 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosolic ribosome IDA
IDA: 通过直接分析推断
23636399 GOA
part of cytosolic small ribosomal subunit IDA
IDA: 通过直接分析推断
8706699 GOA
part of small-subunit processome IDA
IDA: 通过直接分析推断
34516797 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RPS23 蛋白结构

Ribosom_S12_S23

Ribosom_S12_S23: Ribosomal protein S12/S23 (9 - 142)

  • 0
  • 100
  • 143 a.a.
蛋白主名 其他名称

40S ribosomal protein S23

homolog of yeast ribosomal protein S28

RPS23 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
RPS23 P62266 DCC Homo sapiens P43146
Density Sedimentation
20434207
种属内
RPS23 P62266 OGFOD1 Homo sapiens Q8N543
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Brachycephaly, Trichomegaly, And Developmental Delay

BTDD

Macinnes Syndrome

Mcins
Trichomegaly

Long Eyelashes

TCMGLY

Goldstein Hutt Syndrome

Eyelashes, Long

Movie Lashes
Myasthenic Syndrome, Congenital, 3a, Slow-Channel

Congenital Myasthenic Syndrome 3a

CMS3A

Congenital Myasthenic Syndrome 3a, Slow-Channel

Myasthenic Syndrome, Congenital, Type 3a, Slow-Channel
Campylobacteriosis

Campylobacter Infections

Campylobacter Infection

Enteric Campylobacteriosis
Diamond-Blackfan Anemia

Congenital Pure Red Cell Aplasia

Aase Syndrome

Erythrogenesis Imperfecta

Anemia, Diamond-Blackfan

Congenital Hypoplastic Anemia

Aase-Smith Ii Syndrome

Bds

Blackfan-Diamond Anemia

Congenital Prca

Congenital Hypoplastic Anemia, Blackfan-Diamond Type

Dba

Blackfan - Diamond Syndrome

Chronic Constitutional Pure Red Cell Anaemia

Anemia Diamond Blackfan Type

Anemia Congenital Erythroid Hypoplastic

Aregenerative Anemia Chronic Congenital

Blackfan Diamond Syndrome

Red Cell Aplasia, Pure Hereditary

Aase-Smith Syndrome Ii

Bda

Blackfan Diamond Anemia

Blackfan-Diamond Disease

Blackfan-Diamond Syndrome

Chronic Congenital Agenerative Anemia

Congenital Erythroid Hypoplastic Anemia

Congenital Hypoplastic Anemia Of Blackfan And Diamond

Congenital Pure Red Cell Anemia

Hypoplastic Congenital Anemia

Inherited Erythroblastopenia

Pure Hereditary Red Cell Aplasia

Anemia, Hypoplastic, Congenital

Anemia Hypoplastic Congenital

Fanconi Anemia

Constitutional Aplastic Anemia

Diamond-Blackfan Anemia 1

Aase Smith Syndrome 2

Congenital Red Cell Aplasia

Red Cell Aplasia Of Infants

Pure Red Cell Aplasia Of Infants

Congenital Red Cell Aplastic Anaemia

Congenital Pure Red Cell Anaemia

Congenital Erythroid Hypoplasia

Pearson Marrow-Pancreas Syndrome
Autism Spectrum Disorder

Asd

Autism Spectrum Disorders

Autistic Continuum

Pervasive Developmental Disorder

Pervasive Development Disorder

Autistic Behavior

Autistic Disorder

Autistic

Autistic Disorder Of Childhood Onset

Infantile Autism

Childhood Autism

Kanner Syndrome

Pervasive Developmental Delay Nos

Pervasive Developmental Disorder, Not Otherwise Specified
Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12234 RPS23 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris RPS23 VGNC VGNC:53238
Mus musculus RPS23 MGD MGI:1913725
Rattus norvegicus RPS23 RGD RGD:621039
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