2. Gene
  3. DLG2 - Dlg2 discs large MAGUK scaffold protein 2 Gene

DLG2 - Dlg2 discs large MAGUK scaffold protein 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Dlgh2

基因 ID: 64053 | 基因类型: protein coding

关于 DLG2

功能概要

Enables PDZ domain binding activity; protein C-terminus binding activity; and protein Phosphatase binding activity. Involved in neuronal ion channel clustering and receptor clustering. Located in several cellular components, including dendrite; juxtaparanode region of axon; and neuronal cell body. Is active in glutamatergic synapse. Is anchored component of postsynaptic density membrane. Orthologous to human DLG2 (discs large MAGUK scaffold protein 2). [provided by Alliance of Genome Resources, Apr 2022]

DLG2 基因产物(1)

mRNA Protein Name
NM_022282.2 NP_071618.2 disks large homolog 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables PDZ domain binding IPI
IPI: 通过物理相互作用推断
15024025 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
9786987 RGD
enables protein phosphatase binding IPI
IPI: 通过物理相互作用推断
20410104 RGD
enables protein-containing complex binding IPI
IPI: 通过物理相互作用推断
8755482 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in neuronal ion channel clustering IMP
IMP: 通过突变表型推断
8755482 RGD
involved in receptor clustering IMP
IMP: 通过突变表型推断
8755482 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendrite IDA
IDA: 通过直接分析推断
8755482 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
10648730 RGD
located in juxtaparanode region of axon IDA
IDA: 通过直接分析推断
19109503 RGD
located in membrane IDA
IDA: 通过直接分析推断
20089912 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
8755482 RGD
is active in postsynaptic density membrane IDA
IDA: 通过直接分析推断
10648730 RGD
part of voltage-gated potassium channel complex IDA
IDA: 通过直接分析推断
20089912 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

disks large homolog 2

channel-associated protein of synapse-110

chapsyn-110

discs, large homolog 2

disks large 1 tumor suppressor protein-like

postsynaptic density protein PSD-93

synaptic density protein PSD-93

DLG2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Cross Dlg2 Q63622 ATP2B4 Homo sapiens P23634-6
Anti Bait CoIP
11274188
Cross Dlg2 Q63622 CRHR1 Homo sapiens P34998
Anti Tag CoIP
26352593
Cross Dlg2 Q63622 KIF1B Homo sapiens O60333-3
Y2H
12097473
Intra Dlg2 Q63622 Map1a Rattus norvegicus P34926
Pull Down
9786987
Intra Dlg2 Q63622 Map1a Rattus norvegicus P34926
Far-WB
9786987
Intra Dlg2 Q63622 Dgkz Rattus norvegicus O08560
Y2H
19229292
Intra Dlg2 Q63622 Dgkz Rattus norvegicus O08560
Anti Bait CoIP
19229292
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03797 DLG2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens DLG2 NCBI NCBI:1740
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