LHX5 - LIM homeobox 5 Gene

中文名称：LIM 同源框 5

种属: Homo sapiens

关于 LHX5

功能概要

该基因编码属于一个大蛋白质家族的蛋白质，其成员携带 LIM 结构域，这是一个独特的富含半胱氨酸的锌结合结构域。编码的蛋白质可能作为转录调节因子发挥作用，并参与控制前脑的分化和发育。在小鼠中，这种蛋白质对于调节前体细胞增殖和控制海马发育过程中的神经元分化和迁移至关重要。这种蛋白质参与成年小鼠的学习和运动功能。[RefSeq 提供，2008 年 7 月]

This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in the control of differentiation and development of the forebrain. In mice, this protein is essential for the regulation of precursor cell proliferation and the control of neuronal differentiation and migration during hippocampal development. This protein is involved in learning and motor functions in adult mice. [provided by RefSeq, Jul 2008]