SRSF5 - serine and arginine rich splicing factor 5 Gene

中文名称：富丝氨酸和精氨酸的剪接因子 5

种属: Homo sapiens

同用名: HRS; SFRS5; SRP40

关于 SRSF5

功能概要

由该基因编码的蛋白质是富含丝氨酸/精氨酸 (SR) 的 pre-mRNA 剪接因子家族的成员，它构成了剪接体的一部分。这些因子中的每一个都包含一个用于结合 RNA 的 RNA 识别基序 (RRM) 和一个用于结合其他蛋白质的 RS 结构域。 RS 结构域富含丝氨酸和精氨酸残基，可促进不同 SR 剪接因子之间的相互作用。除了对 mRNA 剪接至关重要外，SR 蛋白还显示参与 mRNA 从细胞核输出和翻译。可变剪接导致多个转录本变体。[RefSeq 提供，2016 年 2 月]

The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding Other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]