2. Gene
  3. Gpr88 - G-protein coupled receptor 88 Gene

Gpr88 - G-protein coupled receptor 88 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：G 蛋白偶联受体 88

种属: Mus musculus

同用名: Strg

基因 ID: 64378 | 基因类型: protein coding

关于 Gpr88

Chromosome 3: 116,043,303-116,047,152 reverse strand.GRCm39:CM000996.3

This gene has 3 transcripts (splice variants), 147 orthologues, 55 paralogues and is associated with 31 phenotypes. Biased expression in cortex adult (RPKM 16.3), CNS E18 (RPKM 8.2) and 9 other tissues.

功能概要

该基因编码的蛋白可启动细胞骨架运动活动。参与运动学习。在运动行为的上游或内部行动；神经肌肉过程控制平衡；和神经元动作电位。预计位于多种细胞成分中，包括纤毛；核;和质膜。预计是质膜的组成部分。以多种结构表达，包括消化系统；中枢神经系统;耳朵;泌尿生殖系统；和骨架。与人 GPR88（G 蛋白偶联受体 88）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables cytoskeletal motor activity. Involved in motor learning. Acts upstream of or within locomotory behavior; neuromuscular process controlling balance; and neuronal action potential. Predicted to be located in several cellular components, including cilium; nucleus; and plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; ear; genitourinary system; and skeleton. Orthologous to human GPR88 (G protein-coupled receptor 88). [provided by Alliance of Genome Resources, Apr 2022]

Gpr88 基因产物(8)

mRNA Protein Name
NM_001411424.1 NP_001398353.1 probable G-protein coupled receptor 88
NM_001411426.1 NP_001398355.1 probable G-protein coupled receptor 88
NM_022427.3 NP_071872.1 probable G-protein coupled receptor 88
NM_001411425.1 NP_001398354.1 probable G-protein coupled receptor 88
NM_001411424.1 NP_001398353.1 probable G-protein coupled receptor 88
NM_001411425.1 NP_001398354.1 probable G-protein coupled receptor 88
NM_001411426.1 NP_001398355.1 probable G-protein coupled receptor 88
NM_022427.3 NP_071872.1 probable G-protein coupled receptor 88
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cytoskeletal motor activity IMP
IMP: 通过突变表型推断
26188600 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within locomotory behavior IMP
IMP: 通过突变表型推断
23064379 MGI
involved in motor learning IMP
IMP: 通过突变表型推断
26188600 MGI
acts upstream of or within neuromuscular process controlling balance IMP
IMP: 通过突变表型推断
23064379 MGI
acts upstream of or within neuronal action potential IMP
IMP: 通过突变表型推断
23064379 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Gpr88 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (32 - 346)

7tm_GPCRs

7tm_GPCRs: cd14964 (33 - 57)

7tm_GPCRs

7tm_GPCRs: cd14964 (66 - 88)

7tm_GPCRs

7tm_GPCRs: cd14964 (113 - 135)

7tm_GPCRs

7tm_GPCRs: cd14964 (159 - 175)

7tm_GPCRs

7tm_GPCRs: cd14964 (189 - 212)

7tm_GPCRs

7tm_GPCRs: cd14964 (282 - 304)

7tm_GPCRs

7tm_GPCRs: cd14964 (314 - 339)

  • 0
  • 100
  • 200
  • 300
  • 384 a.a.
蛋白主名 其他名称

probable G-protein coupled receptor 88

striatum-specific G-protein coupled receptor

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-100013A1 (1R,2R)-2-PCCA hydrochloride 98.08% 否
HY-100013C 2-PCCA hydrochloride 99.63% 否
HY-112612A RTI-13951-33 hydrochloride 98.56% 否
HY-156771 GPR88-IN-1 Inhibitor 99.54% 否
HY-112612 RTI-13951-33 / 否
HY-156772 GPR88 agonist 2 Agonist 99.57% 否
HY-162660 BI-9508 Agonist / 否
HY-163096 GPR88 agonist 3 Agonist / 否
HY-167856 RTI-122 Agonist / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gpr88 NCBI NCBI:54112
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