ATG3 - autophagy related 3 Gene

中文名称：自噬相关 3

种属: Homo sapiens

同用名: APG3; APG3L; hApg3; PC3-96; APG3-LIKE

关于 ATG3

功能概要

该基因编码泛素样结合酶，是参与自噬的泛素化样系统的组成部分，自噬是真核细胞中细胞质成分的降解、周转和再循环过程。已知这种蛋白质在细胞死亡期间的自噬调节中发挥作用。该基因的假基因位于 20 号染色体上。可变剪接导致编码不同亚型的多个转录变体。[RefSeq 提供，2013 年 7 月]

This gene encodes a ubiquitin-like-conjugating Enzyme and is a component of ubiquitination-like systems involved in Autophagy, the process of degradation, turnover and recycling of cytoplasmic constituents in eukaryotic cells. This protein is known to play a role in regulation of Autophagy during cell death. A pseudogene of this gene is located on chromosome 20. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]