2. Gene
  3. ZG16 - zymogen granule protein 16 Gene

ZG16 - zymogen granule protein 16 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：酶原颗粒蛋白 16

种属: Homo sapiens

同用名: JCLN; JCLN1; ZG16A

基因 ID: 653808 | 基因类型: protein coding

关于 ZG16

Cytogenetic location: 16p11.2 Genomic coordinates (GRCh38): 16:29,778,256-29,782,973 (from NCBI)

This gene has 1 transcript (splice variant) and 128 orthologues. Biased expression in colon (RPKM 333.1), small intestine (RPKM 82.8) and 1 other tissue.

功能概要

预测启用碳水化合物结合活性和肽聚糖结合活性。预计参与蛋白质运输。预计在对革兰氏阳性细菌的防御反应上游或防御反应内起作用，并抑制共生体进入宿主。位于高尔基体腔和含胶原蛋白的细胞外基质中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable carbohydrate binding activity and peptidoglycan binding activity. Predicted to be involved in protein transport. Predicted to act upstream of or within defense response to Gram-positive bacterium and suppression of symbiont entry into host. Located in Golgi lumen and collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Apr 2022]

ZG16 基因产物(1)

mRNA Protein Name
NM_152338.4 NP_689551.3 zymogen granule membrane protein 16 precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi lumen IDA
IDA: 通过直接分析推断
17307141 GOA
located in collagen-containing extracellular matrix IDA
IDA: 通过直接分析推断
17307141 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ZG16 蛋白结构

Jacalin

Jacalin: Jacalin-like lectin domain (41 - 158)

  • 0
  • 100
  • 167 a.a.
蛋白主名 其他名称

zymogen granule membrane protein 16

jacalin-like lectin domain containing

ZG16 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ZG16 O60844 UBQLN1 Homo sapiens Q9UMX0-2
Validated Y2H
25416956
种属内
ZG16 O60844 UBE2I Homo sapiens Q7KZS0
Y2H Prey Pooling
32296183
种属内
ZG16 O60844 UBE2I Homo sapiens Q7KZS0
Y2H Array
32296183
种属内
ZG16 O60844 UBE2I Homo sapiens Q7KZS0
Validated Y2H
32296183
种属内
ZG16 O60844 PUF60 Homo sapiens Q9UHX1
Y2H Prey Pooling
25416956
种属内
ZG16 O60844 PUF60 Homo sapiens Q9UHX1-2
Validated Y2H
32296183
种属内
ZG16 O60844 CTNNA3 Homo sapiens Q9UI47-2
Validated Y2H
32296183
种属内
ZG16 O60844 ASPH Homo sapiens Q12797-6
Validated Y2H
32296183
种属内
ZG16 O60844 SGTA Homo sapiens O43765
Y2H Array
32296183
种属内
ZG16 O60844 SGTA Homo sapiens O43765
Y2H Prey Pooling
32296183
种属内
ZG16 O60844 UBQLN1 Homo sapiens Q9UMX0
Y2H Prey Pooling
25416956
种属内
ZG16 O60844 UBQLN1 Homo sapiens Q9UMX0
Y2H Array
16713569
种属内
ZG16 O60844 UBQLN1 Homo sapiens Q9UMX0
Y2H Prey Pooling
32296183
种属内
ZG16 O60844 UBQLN1 Homo sapiens Q9UMX0
Validated Y2H
32296183
种属内
ZG16 O60844 UBQLN1 Homo sapiens Q9UMX0
Y2H Array
25416956
种属内
ZG16 O60844 UBQLN1 Homo sapiens Q9UMX0
Y2H Array
32296183
种属内
ZG16 O60844 SGTB Homo sapiens Q96EQ0
Y2H Prey Pooling
32296183
种属内
ZG16 O60844 SGTB Homo sapiens Q96EQ0
Validated Y2H
32296183
种属内
ZG16 O60844 SGTB Homo sapiens Q96EQ0
Y2H Array
32296183
种属内
ZG16 O60844 GLYCTK Homo sapiens Q8IVS8
Validated Y2H
32296183
种属内
ZG16 O60844 KCNIP3 Homo sapiens Q9Y2W7
Y2H Prey Pooling
32296183
种属内
ZG16 O60844 KCNIP3 Homo sapiens Q9Y2W7
Validated Y2H
32296183
种属内
ZG16 O60844 KCNIP3 Homo sapiens Q9Y2W7
Y2H Array
32296183
种属内
ZG16 O60844 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
种属内
ZG16 O60844 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
种属内
ZG16 O60844 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 ZG16 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71037 ZG16 Protein, Human (HEK293, His) O60844 (N17-C167) ≥95%
HY-P77285 ZG16 Protein, Human (HEK293, Fc) O60844 (N17-C167) ≥95%

关联疾病

疾病名称 别名
Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome 1

Eec Syndrome

Rudiger Syndrome 1

Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip-Palate Syndrome 1

EEC1

Eec Syndrome 1

Eec Syndrome-1

Walker-Clodius Syndrome

Ectrodactyly-Ectodermal Dysplasia-Cleft Lip/Palate Syndrome

Eec

Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip-Palate Syndrome

Ectrodactyly-Ectodermal Dysplasia-Clefting Syndrome

Ectrodactyly-Cleft Lip/Palate Syndrome

Ectrodactyly-Ectodermal Dysplasia-Cleft Lip/Cleft Palate

Ectrodactyly-Ectodermal Dysplasia-Clefting Syndrome

Ectrodactyly, Ectodermal Dysplasia, Clefting Syndrome

Ectrodactyly-Cleft Lip-Palate Syndrome

Ectrodactyly, Ectodermal Dysplasia, And Cleft Lip/Palate Syndrome
Spondylocostal Dysostosis 5

Spondylothoracic Dysostosis

SCDO5

Jarcho-Levin Syndrome

Scoliosis, Congenital, With Or Without Rib Anomalies

Tacs

Spondylocostal Dysplasia

Costovertebral Segmentation Anomalies

Spondylocostal Dysostosis 1

Spondylocostal Dysostosis

Spondylothoracic Dysplasia

Scdo1

Spondylocostal Dysostosis 1 Autosomal Recessive

Costovertebral Dysplasia

Scdo

Std

Autosomal Dominant Spondylocostal Dysostosis

Autosomal Dominant Spondylocostal Dysplasia

Doid:0112363

Spondylocostal Dysostosis 4, Autosomal Dominant
Colon Mucinous Adenocarcinoma

Colonic Mucinous Adenocarcinoma

Mucinous Adenocarcinoma Of The Colon
Episodic Kinesigenic Dyskinesia 1

Paroxysmal Kinesigenic Choreoathetosis

Paroxysmal Kinesigenic Dyskinesia

Dystonia 10

Familial Paroxysmal Kinesigenic Dyskinesia

Episodic Kinesigenic Dyskinesia

EKD1

Pkc

Pkd

Dyt10

Familial Pkd

Paroxysmal Kinesigenic Choreathetosis

Familial Paroxysmal Dystonia

Dystonia, Familial Paroxysmal

Dyt-Prrt2

Dystonia, Type 10
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16063 ZG16 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS16064 ZG16B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta ZG16 VGNC VGNC:104766
Bos taurus ZG16 VGNC VGNC:37180
Canis familiaris ZG16 VGNC VGNC:48629
Rattus norvegicus ZG16 RGD RGD:620346
Mus musculus ZG16 MGD MGI:1916286
Others ZG16 NCBI
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