2. Gene
  3. Clstn1 - calsyntenin 1 Gene

Clstn1 - calsyntenin 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Cst-1; Cstn1; 1810034E21Rik

基因 ID: 65945 | 基因类型: protein coding

关于 Clstn1

功能概要

Predicted to enable X11-like protein binding activity; amyloid-beta binding activity; and Kinesin binding activity. Involved in neurotransmitter receptor transport to postsynaptic membrane; regulation of synapse maturation; and vesicle-mediated transport in synapse. Acts upstream of or within positive regulation of synapse assembly; positive regulation of synaptic transmission; and regulation of cell growth. Located in several cellular components, including postsynaptic density; postsynaptic endosome; and postsynaptic membrane. Is integral component of membrane. Is active in glutamatergic synapse. Is expressed in central nervous system; intestine; and retina. Orthologous to human CLSTN1 (calsyntenin 1). [provided by Alliance of Genome Resources, Apr 2022]

Clstn1 基因产物(2)

mRNA Protein Name
NM_001290989.1 NP_001277918.1 calsyntenin-1 isoform 2 precursor
NM_023051.5 NP_075538.1 calsyntenin-1 isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
17332754 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in neurotransmitter receptor transport to postsynaptic membrane IDA
IDA: 通过直接分析推断
24966372 MGI
involved in neurotransmitter receptor transport to postsynaptic membrane IEP
IEP: 通过表达模式推断
24966372 MGI
involved in neurotransmitter receptor transport to postsynaptic membrane IMP
IMP: 通过突变表型推断
24966372 MGI
acts upstream of or within positive regulation of synapse assembly IGI
IGI: 通过遗传相互作用推断
24613359 MGI
acts upstream of or within positive regulation of synaptic transmission IGI
IGI: 通过遗传相互作用推断
24613359 MGI
acts upstream of or within regulation of cell growth IGI
IGI: 通过遗传相互作用推断
24613359 MGI
involved in regulation of synapse maturation IDA
IDA: 通过直接分析推断
24966372 MGI
involved in regulation of synapse maturation IEP
IEP: 通过表达模式推断
24966372 MGI
involved in regulation of synapse maturation IMP
IMP: 通过突变表型推断
24966372 MGI
involved in vesicle-mediated transport in synapse IDA
IDA: 通过直接分析推断
24966372 MGI
involved in vesicle-mediated transport in synapse IEP
IEP: 通过表达模式推断
24966372 MGI
involved in vesicle-mediated transport in synapse IMP
IMP: 通过突变表型推断
24966372 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
24613359 MGI
located in extracellular region IDA
IDA: 通过直接分析推断
11161476 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
24966372 MGI
is active in glutamatergic synapse IEP
IEP: 通过表达模式推断
24966372 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
24966372 MGI
located in membrane IDA
IDA: 通过直接分析推断
11161476 MGI
located in postsynaptic density IDA
IDA: 通过直接分析推断
24613359 MGI
is active in postsynaptic endosome IDA
IDA: 通过直接分析推断
24966372 MGI
located in postsynaptic membrane IDA
IDA: 通过直接分析推断
11161476 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

calsyntenin-1

alc-alpha

alcadein alpha

Clstn1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Clstn1 Q9EPL2 Klc1 Mus musculus Q8CD76
Y2H
17332754
种属内
Clstn1 Q9EPL2 Klc1 Mus musculus Q8CD76
Anti Bait CoIP
17332754
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02840 CLSTN1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Clstn1 NCBI NCBI:22883
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