2. Gene
  3. CAPN15 - calpain 15 Gene

CAPN15 - calpain 15 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：钙蛋白酶 15

种属: Homo sapiens

同用名: OGIN; SOLH

基因 ID: 6650 | 基因类型: protein coding

关于 CAPN15

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:527,712-554,636 (from NCBI)

This gene has 8 transcripts (splice variants), 1 gene allele, 236 orthologues, 20 paralogues and is associated with 1 phenotype. Broad expression in colon (RPKM 5.1), spleen (RPKM 4.7) and 25 other tissues.

功能概要

该基因编码一种含有锌指样重复序列和钙蛋白酶样蛋白酶结构域的蛋白质。编码的蛋白质可以作为转录因子、RNA 结合蛋白或视觉系统发育过程中的蛋白质-蛋白质相互作用发挥作用。[RefSeq 提供，2008 年 7 月]

This gene encodes a protein containing zinc-finger-like repeats and a calpain-like protease domain. The encoded protein may function as a transcription factor, RNA-binding protein, or in protein-protein interactions during visual system development. [provided by RefSeq, Jul 2008]

CAPN15 基因产物(1)

mRNA Protein Name
NM_005632.3 NP_005623.1 calpain-15
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CAPN15 蛋白结构

zf-RanBP

zf-RanBP: Zn-finger in Ran binding protein and others (5 - 30)

zf-RanBP

zf-RanBP: Zn-finger in Ran binding protein and others (145 - 170)

zf-RanBP

zf-RanBP: Zn-finger in Ran binding protein and others (412 - 438)

Peptidase_C2

Peptidase_C2: Calpain family cysteine protease (488 - 792)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1086 a.a.
蛋白主名 其他名称

calpain-15

small optic lobes homolog

CAPN15 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
CAPN15 O75808 TRAF2 Homo sapiens Q12933
Validated Y2H
32296183
种属内
CAPN15 O75808 TRAF2 Homo sapiens Q12933
Y2H Prey Pooling
32296183
种属内
CAPN15 O75808 TRAF2 Homo sapiens Q12933
Y2H Array
32296183
种属内
CAPN15 O75808 RNF216 Homo sapiens Q9NWF9
Y2H Array
32296183
种属内
CAPN15 O75808 RNF216 Homo sapiens Q9NWF9
Y2H Prey Pooling
32296183
种属内
CAPN15 O75808 RNF216 Homo sapiens Q9NWF9
Validated Y2H
32296183
种属内
CAPN15 O75808 DAZAP2 Homo sapiens Q15038
Y2H Prey Pooling
32296183
种属内
CAPN15 O75808 DAZAP2 Homo sapiens Q15038
Validated Y2H
32296183
种属内
CAPN15 O75808 DAZAP2 Homo sapiens Q15038
Y2H Array
32296183
种属内
CAPN15 O75808 UBQLN2 Homo sapiens Q9UHD9
Y2H Prey Pooling
32296183
种属内
CAPN15 O75808 UBQLN2 Homo sapiens Q9UHD9
Validated Y2H
32296183
种属内
CAPN15 O75808 UBQLN2 Homo sapiens Q9UHD9
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Oculogastrointestinal Neurodevelopmental Syndrome

OGIN

Oculogastrointestinal-Neurodevelopmental Syndrome

Ogin Syndrome
Coloboma, Ocular, Autosomal Dominant

Coloboma, Ocular

Coloboma Of Iris, Choroid, And Retina

Coi

Coloboma, Uveoretinal

COAD

Ocular Coloboma

Uveoretinal Coloboma

Chronic Obstructive Airway Disease
Coloboma Of Macula

Coloboma

Congenital Ocular Coloboma

Microphthalmia, Isolated, With Coloboma

Agenesis Of Macula

Hereditary Macular Coloboma

Ocular Coloboma

Coloboma Of Eye

Macular Coloboma

Uveoretinal Coloboma
Spastic Hemiplegia

Spastic Hemiplegic Cerebral Palsy

Hemiplegic Cerebral Palsy

Congenital Hemiplegia

Hemiplegic Infantile Cerebral Palsy

Cerebral Palsy Spastic Hemiplegic

Spastic Hemiplegia Cerebral Palsy

Hemiplegia, Spastic
Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly
Microphthalmia

Microphthalmos

Isolated Anophthalmia-Microphthalmia Syndrome

Isolated Microphthalmia-Anophthalmia-Coloboma

Simple Microphthalmos

Clinical Anophthalmia

Isolated Anophthalmia - Microphthalmia

Isolated Pure Microphthalmia

Mac Spectrum

Microphthalmia-Anophthalmia-Coloboma Spectrum

Primitive Anophthalmia

Globe Of Eye Small

Small Eyeball

Hypoplasia Of Eye

Isolated Nanophthalmos

Rudimentary Eye

Dysplasia Of Eye
Heart Disease

Heart Failure

Congenital Heart Disease

Heart Diseases

Congenital Heart Defects

Congenital Heart Defect

Heart Malformation

Congenital Anomaly Of Heart

Heart Defect

Heart-Congenital Defect

Congenital Heart Disorder

Heart Defects Congenital

Heart Defects, Congenital

Heart Defects

Heart Disease, Congenital

Disease, Heart, Congenital

Congestive Heart Failure
Focal Hand Dystonia

Organic Writer'S Cramp

Dystonia, Focal, Task-Specific
Spastic Cerebral Palsy

Palsy, Cerebral, Spastic

Infantile Hemiplegia Nos

Postnatal Infantile Hemiplegia Nos

Congenital Spastic Hemiplegia

Spastic Hemiplegic Cerebral Palsy

Congenital Hemiplegia Nos

Hemiplegic Cerebral Palsy

Hemiplegic Infantile Cerebral Palsy
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS01888 CAPN15 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus CAPN15 VGNC VGNC:26746
Macaca mulatta CAPN15 VGNC VGNC:70470
Mus musculus CAPN15 MGD MGI:1355075
Canis familiaris CAPN15 VGNC VGNC:38703
Rattus norvegicus CAPN15 RGD RGD:1306514
Felis catus CAPN15 VGNC VGNC:60353
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