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  2. HSPA13 - heat shock protein family A (Hsp70) member 13 Gene

HSPA13 - heat shock protein family A (Hsp70) member 13 Gene

中文名称:热休克蛋白家族 A (Hsp70) 成员 13

种属: Homo sapiens

同用名: STCH

基因 ID: 6782 | 基因类型: protein coding

关于 HSPA13

Cytogenetic location: 21q11.2 Genomic coordinates (GRCh38): 21:14,371,115-14,383,146 (from NCBI)

This gene has 2 transcripts (splice variants), 205 orthologues and 13 paralogues. Ubiquitous expression in brain (RPKM 23.3), thyroid (RPKM 21.7) and 25 other tissues.

功能概要

由该基因编码的蛋白质是热休克蛋白 70 家族的成员,被发现与微粒体相关。该蛋白质家族的成员在细胞溶质和分泌蛋白的加工以及去除变性或错误折叠的蛋白质方面发挥作用。编码的蛋白质包含一个 ATPase 结构域,并已被证明与一种泛素样蛋白质相关。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is a member of the heat shock protein 70 family and is found associated with microsomes. Members of this protein family play a role in the processing of cytosolic and secretory proteins, as well as in the removal of denatured or incorrectly-folded proteins. The encoded protein contains an ATPase domain and has been shown to associate with a ubiquitin-like protein. [provided by RefSeq, Jul 2008]

HSPA13 基因产物(1)

mRNA Protein Name
NM_006948.5 NP_008879.3 heat shock 70 kDa protein 13 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

HSPA13 蛋白结构

HSP70

HSP70: Hsp70 protein (33 - 317)

HSP70

HSP70: Hsp70 protein (358 - 450)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 471 a.a.
蛋白主名 其他名称

heat shock 70 kDa protein 13

heat shock protein 70kDa family, member 13

HSPA13 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
HSPA13 P48723 UBQLN1 Homo sapiens Q9UMX0-2 25416956
种属内
HSPA13 P48723 UBQLN1 Homo sapiens Q9UMX0-2 25416956
种属内
HSPA13 P48723 UBQLN1 Homo sapiens Q9UMX0-2 35914814
种属内
HSPA13 P48723 UBQLN1 Homo sapiens Q9UMX0-2 25416956
种属内
HSPA13 P48723 CRYGA Homo sapiens Q24JT5 32296183
种属内
HSPA13 P48723 CRYGA Homo sapiens Q24JT5 32296183
种属内
HSPA13 P48723 CRYGA Homo sapiens Q24JT5 32296183
种属内
HSPA13 P48723 B4GALT5 Homo sapiens O43286 28514442
种属内
HSPA13 P48723 SGTA Homo sapiens O43765 32296183
种属内
HSPA13 P48723 SGTA Homo sapiens O43765 25416956
种属内
HSPA13 P48723 SGTA Homo sapiens O43765 32296183
种属内
HSPA13 P48723 SGTA Homo sapiens O43765 25416956
种属内
HSPA13 P48723 UBQLN4 Homo sapiens Q9NRR5 16713569
种属内
HSPA13 P48723 UBQLN4 Homo sapiens Q9NRR5 35914814
种属内
HSPA13 P48723 UBQLN1 Homo sapiens Q9UMX0 25416956
种属内
HSPA13 P48723 UBQLN1 Homo sapiens Q9UMX0 32296183
种属内
HSPA13 P48723 UBQLN1 Homo sapiens Q9UMX0 32296183
种属内
HSPA13 P48723 UBQLN1 Homo sapiens Q9UMX0 25416956
种属内
HSPA13 P48723 UBQLN1 Homo sapiens Q9UMX0 32296183
种属内
HSPA13 P48723 UBQLN1 Homo sapiens Q9UMX0 16189514
种属内
HSPA13 P48723 SGTB Homo sapiens Q96EQ0 35914814
种属内
HSPA13 P48723 SGTB Homo sapiens Q96EQ0 32296183
种属内
HSPA13 P48723 SGTB Homo sapiens Q96EQ0 32296183
种属内
HSPA13 P48723 SGTB Homo sapiens Q96EQ0 32296183
种属内
HSPA13 P48723 UBQLN2 Homo sapiens Q9UHD9 35914814
种属内
HSPA13 P48723 UBQLN2 Homo sapiens Q9UHD9 32296183
种属内
HSPA13 P48723 UBQLN2 Homo sapiens Q9UHD9 32296183
种属内
HSPA13 P48723 UBQLN2 Homo sapiens Q9UHD9 32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Bartter Syndrome, Type 1, Antenatal

Hyperprostaglandin E Syndrome 1

Bartter Disease Type 1

BARTS1

Bartter Syndrome, Type 1

Bartter Syndrome Type 1

Hypokalemic Alkalosis With Hypercalciuria Antenatal 1

Hypokalemic Alkalosis With Hypercalciuria 1, Antenatal

Bartter Syndrome Type 1 Antenatal

Hypokalemic Alkalosis With Hypercalciuria 1 Antenatal

Bartter Syndrome Antenatal Type 1

Antenatal Bartter Syndrome Type 1

Bartter Syndrome Type I

Bartter Syndrome 1, Antenatal

Abs1

Antenatal Bartter Syndrome 1

Bs1

Bartter Syndrome, Antenatal Type 1

Antley-Bixler Syndrome With Genital Anomalies And Disordered Steroidogenesis

Deafness, Autosomal Dominant 28

DFNA28

Autosomal Dominant Nonsyndromic Deafness 28

Autosomal Dominant Deafness 28

Deafness, Autosomal Dominant, 28

Non-Syndromic Neurosensory Deafness Autosomal Dominant Type 28

Non-Syndromic Sensorineural Deafness Autosomal Dominant Type 28

Deafness, Autosomal Dominant, Type 28

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus HSPA13 VGNC VGNC:102758
Bos taurus HSPA13 VGNC VGNC:53581
Macaca mulatta HSPA13 VGNC VGNC:81327
Rattus norvegicus HSPA13 RGD RGD:3775
Mus musculus HSPA13 MGD MGI:1309463
Canis familiaris HSPA13 VGNC VGNC:53026
Others HSPA13 NCBI