1. Gene
  2. SYPL1 - synaptophysin like 1 Gene

SYPL1 - synaptophysin like 1 Gene

中文名称:突触蛋白样 1

种属: Homo sapiens

同用名: SYPL; H-SP1

基因 ID: 6856 | 基因类型: protein coding

关于 SYPL1

Cytogenetic location: 7q22.3 Genomic coordinates (GRCh38): 7:106,090,505-106,112,576 (from NCBI)

This gene has 10 transcripts (splice variants), 236 orthologues and 3 paralogues. Ubiquitous expression in thyroid (RPKM 63.3), esophagus (RPKM 56.9) and 25 other tissues.

功能概要

预计参与化学突触传递。位于细胞外外泌体。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in chemical synaptic transmission. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

SYPL1 基因产物(13)

mRNA Protein Name
NM_001381910.1 NP_001368839.1 synaptophysin-like protein 1 isoform c
NM_001381911.1 NP_001368840.1 synaptophysin-like protein 1 isoform d
NM_001381912.1 NP_001368841.1 synaptophysin-like protein 1 isoform e
NM_001381913.1 NP_001368842.1 synaptophysin-like protein 1 isoform f
NM_001381915.1 NP_001368844.1 synaptophysin-like protein 1 isoform g
NM_001381916.1 NP_001368845.1 synaptophysin-like protein 1 isoform h
NM_001381917.1 NP_001368846.1 synaptophysin-like protein 1 isoform i precursor
NM_001381918.1 NP_001368847.1 synaptophysin-like protein 1 isoform j
NM_001381919.1 NP_001368848.1 synaptophysin-like protein 1 isoform j
NM_001381920.1 NP_001368849.1 synaptophysin-like protein 1 isoform k
NM_001381921.1 NP_001368850.1 synaptophysin-like protein 1 isoform k
NM_006754.5 NP_006745.1 synaptophysin-like protein 1 isoform a
NM_182715.4 NP_874384.1 synaptophysin-like protein 1 isoform b
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
29547901 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SYPL1 蛋白结构

MARVEL

MARVEL: Membrane-associating domain (29 - 231)

  • 0
  • 100
  • 200
  • 259 a.a.
蛋白主名 其他名称

synaptophysin-like protein 1

pantophysin

SYPL1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SYPL1 Q16563 TEX44 Homo sapiens Q53QW1
Validated Y2H
32296183
种属内
SYPL1 Q16563 CIB3 Homo sapiens Q96Q77
Validated Y2H
32296183
种属内
SYPL1 Q16563 TARS2 Homo sapiens Q9BW92
Validated Y2H
32296183
种属内
SYPL1 Q16563 ARFGAP3 Homo sapiens Q9NP61
Validated Y2H
32296183
种属内
SYPL1 Q16563 RBFA Homo sapiens Q8N0V3
Validated Y2H
32296183
种属内
SYPL1 Q16563 PBX3 Homo sapiens Q96AL5
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

SYPL1 抗体

目录号 产品名 应用 反应物种
HY-P82379 Synaptophysin Like Protein 1 Antibody (YA2124) WB, IHC-P Human

关联疾病

疾病名称 别名
Intellectual Developmental Disorder, Autosomal Dominant 35

MRD35

Intellectual Disability-Macrocephaly-Hypotonia-Behavioral Abnormalities Syndrome

Autosomal Dominant Non-Syndromic Intellectual Disability 35

Mental Retardation, Autosomal Dominant 35

Autosomal Dominant Intellectual Developmental Disorder 35

Autosomal Dominant Mental Retardation 35

Mental Retardation, Autosomal Dominant, Type 35

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus SYPL1 VGNC VGNC:53679
Mus musculus SYPL1 MGD MGI:108081
Canis familiaris SYPL1 VGNC VGNC:47039
Macaca mulatta SYPL1 VGNC VGNC:78073
Rattus norvegicus SYPL1 RGD RGD:1359569