1. Gene
  2. Usp46 - ubiquitin specific peptidase 46 Gene

Usp46 - ubiquitin specific peptidase 46 Gene

种属: Mus musculus

同用名: 1190009E20Rik; 2410018I08Rik

基因 ID: 69727 | 基因类型: protein coding

关于 Usp46

功能概要

Enables Deubiquitinase activity. Involved in regulation of GABAergic synaptic transmission. Acts upstream of or within several processes, including adult feeding behavior; behavioral fear response; and behavioral response to ethanol. Predicted to be active in cytosol and nucleus. Is expressed in pancreas epithelium. Orthologous to human USP46 (ubiquitin specific peptidase 46). [provided by Alliance of Genome Resources, Apr 2022]

Usp46 基因产物(1)

mRNA Protein Name
NM_177561.3 NP_808229.1 ubiquitin carboxyl-terminal hydrolase 46
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables deubiquitinase activity IDA
IDA: 通过直接分析推断
26811477 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adult feeding behavior IMP
IMP: 通过突变表型推断
23472206 MGI
acts upstream of or within behavioral fear response IMP
IMP: 通过突变表型推断
22720038 MGI
acts upstream of or within behavioral response to ethanol IMP
IMP: 通过突变表型推断
23472206 MGI
acts upstream of or within protein deubiquitination IDA
IDA: 通过直接分析推断
26811477 MGI
involved in regulation of synaptic transmission, GABAergic IMP
IMP: 通过突变表型推断
19465912 MGI
acts upstream of or within righting reflex IMP
IMP: 通过突变表型推断
23472206 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ubiquitin carboxyl-terminal hydrolase 46

deubiquitinating enzyme 46

ubiquitin specific protease 46

ubiquitin thioesterase 46

ubiquitin thiolesterase 46

ubiquitin-specific-processing protease 46

重组 Usp46 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77277 USP46 Protein, Human/Mouse (sf9) P62069 (M1-E366) ≥95%
HY-P77278 USP46 Protein, Human/Mouse (sf9, SUMO) P62069 (M1-E366) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Usp46 NCBI NCBI:64854