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  2. TCTA - T cell leukemia translocation altered Gene

TCTA - T cell leukemia translocation altered Gene

中文名称:T 细胞白血病易位改变

种属: Homo sapiens

基因 ID: 6988 | 基因类型: protein coding

关于 TCTA

Cytogenetic location: 3p21.31 Genomic coordinates (GRCh38): 3:49,412,423-49,416,476 (from NCBI)

This gene has 6 transcripts (splice variants) and 174 orthologues. Ubiquitous expression in thyroid (RPKM 27.1), kidney (RPKM 21.0) and 25 other tissues.

功能概要

参与破骨细胞分化和破骨细胞融合的负调控。预计是膜的组成部分。 [由基因组资源联盟提供,2022 年 4 月]

Involved in negative regulation of osteoclast differentiation and osteoclast fusion. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TCTA 基因产物(1)

mRNA Protein Name
NM_022171.3 NP_071503.1 T-cell leukemia translocation-altered gene protein
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of osteoclast differentiation IDA
IDA: 通过直接分析推断
19560569 GOA
involved in osteoclast fusion IDA
IDA: 通过直接分析推断
19560569 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

TCTA 蛋白结构

T_cell_tran_alt

T_cell_tran_alt: T-cell leukemia translocation-altered (18 - 103)

  • 0
  • 103 a.a.
蛋白主名 其他名称

T-cell leukemia translocation-altered gene protein

T-cell leukemia translocation-associated gene protein

TCTA 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TCTA P57738 SLC35A1 Homo sapiens P78382
Validated Y2H
32296183
种属内
TCTA P57738 CMTM7 Homo sapiens Q96FZ5
Validated Y2H
32296183
种属内
TCTA P57738 YIPF6 Homo sapiens Q96EC8
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Leukemia

Leukemias

Leukaemia, Unspecified, Without Mention Of Remission

Aleukemic Leukaemia

Chronic Leukaemia

Subacute Leukaemia

Leukaemia Disorder

Leukaemia Nos

Cataract 34, Multiple Types

Cataract, Autosomal Recessive Congenital 3

Cataract 34 Multiple Types

CTRCT34

Catc3

Cataract 34, Multiple Types, With Or Without Microcornea

Autosomal Recessive Congenital Cataract 3

Cataract 34 Multiple Types With Or Without Microcornea

Cataract, Multiple Types, Type 34

T-Cell Acute Lymphoblastic Leukemia

T-Cell Leukemia

Acute T Cell Leukemia

Precursor T Lymphoblastic Leukemia

Precursor T-Lymphoblastic Lymphoma/Leukemia

T Acute Lymphoblastic Leukemia

T-Cell Acute Lymphocytic Leukaemia

T-Cell Lymphoblastic Leukemia/Lymphoma

Leukemia T-Cell

Leukemia, T-Cell

Leukemia, Acute, Lymphoblastic, T-Cell

Leukemia, T-Cell Acute Lymphoblastic

Leukemia, Acute T-Cell

Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Precursor T-Cell Lymphoblastic Lymphoma

Precursor T Cell Lymphoblastic Leukemia/Lymphoblastic Lymphoma

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus TCTA RGD RGD:1359333
Mus musculus TCTA MGD MGI:1918829