2. Gene
  3. TNP2 - transition protein 2 Gene

TNP2 - transition protein 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：过渡蛋白 2

种属: Homo sapiens

同用名: TP2

基因 ID: 7142 | 基因类型: protein coding

关于 TNP2

Cytogenetic location: 16p13.13 Genomic coordinates (GRCh38): 16:11,267,857-11,269,325 (from NCBI)

This gene has 2 transcripts (splice variants) and 66 orthologues. Restricted expression toward testis (RPKM 12.9).

功能概要

预测可启用锌离子结合活性。预计参与蛋白质加工的正调控；单一施肥；和精子发生，染色体蛋白质的交换。预计在精子与透明带和带鞭毛的精子运动的结合活性的上游或内部起作用。预测位于核内。预计是核小体的一部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable zinc ion binding activity. Predicted to be involved in positive regulation of protein processing; single fertilization; and spermatogenesis, exchange of chromosomal proteins. Predicted to act upstream of or within binding activity of sperm to zona pellucida and flagellated sperm motility. Predicted to be located in nucleus. Predicted to be part of nucleosome. [provided by Alliance of Genome Resources, Apr 2022]

TNP2 基因产物(1)

mRNA Protein Name
NM_005425.5 NP_005416.1 nuclear transition protein 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
31515488 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TNP2 蛋白结构

TP2

TP2: Nuclear transition protein 2 (1 - 138)

  • 0
  • 100
  • 138 a.a.
蛋白主名 其他名称

nuclear transition protein 2

TP-2

TNP2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TNP2 Q05952 KRTAP10-8 Homo sapiens P60410
Y2H Array
32296183
种属内
TNP2 Q05952 KRTAP10-8 Homo sapiens P60410
Y2H Prey Pooling
32296183
种属内
TNP2 Q05952 KRTAP10-9 Homo sapiens P60411
Y2H Prey Pooling
32296183
种属内
TNP2 Q05952 KRTAP10-9 Homo sapiens P60411
Y2H Array
32296183
种属内
TNP2 Q05952 KRTAP12-3 Homo sapiens P60328
Y2H Array
32296183
种属内
TNP2 Q05952 KRTAP12-3 Homo sapiens P60328
Y2H Prey Pooling
32296183
种属内
TNP2 Q05952 KRTAP1-1 Homo sapiens Q07627
Y2H Prey Pooling
32296183
种属内
TNP2 Q05952 KRTAP1-1 Homo sapiens Q07627
Validated Y2H
32296183
种属内
TNP2 Q05952 KRTAP1-1 Homo sapiens Q07627
Y2H Array
32296183
种属内
TNP2 Q05952 KRTAP2-4 Homo sapiens Q9BYR9
Validated Y2H
32296183
种属内
TNP2 Q05952 KRTAP2-4 Homo sapiens Q9BYR9
Y2H Array
32296183
种属内
TNP2 Q05952 KRTAP2-4 Homo sapiens Q9BYR9
Y2H Prey Pooling
32296183
种属内
TNP2 Q05952 MDFI Homo sapiens Q99750
Validated Y2H
32296183
种属内
TNP2 Q05952 MDFI Homo sapiens Q99750
Y2H Array
32296183
种属内
TNP2 Q05952 MDFI Homo sapiens Q99750
Y2H Prey Pooling
32296183
种属内
TNP2 Q05952 APPBP2 Homo sapiens Q92624
Y2H Prey Pooling
32296183
种属内
TNP2 Q05952 APPBP2 Homo sapiens Q92624
Y2H Array
32296183
种属内
TNP2 Q05952 APPBP2 Homo sapiens Q92624
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Male Infertility

Infertility, Male

Infertility Male

Male Sterility

Absolute Infertility
Spermatogenic Failure

Azoospermia

Spgf

Spermatogenic Failure, Susceptibility To

Absent Sperm

Aspermatogenesis

Infertility Due To Azoospermia

Hypospermatogenesis

Azoospermatism
Epididymo-Orchitis
Infertility
Oligoasthenoteratozoospermia

Oat

Oligoasthenoteratospermia
Embryonal Testis Carcinoma

Testicular Embryonal Carcinoma

Embryonal Carcinoma Of Testis

Embryonal Carcinoma Of The Testis
Pelvic Varices

Varix Of Pelvis

Pelvic Varicose Vein
Oligospermia
Cryptorchidism, Unilateral Or Bilateral

Cryptorchidism

Undescended Testicle

Undescended Testis

Cryptorchism

Undescended Testicles

CRYPTO

Impaired Testicular Descent

Cryptosporidiosis

Retained Testis

Unilateral Cryptorchidism

Unilateral Undescended Testis

Nondescent Unilateral Testicle

Unilateral Cryptorchism

Ectopic Testis, Unilateral

Bilateral Cryptorchidism

Bilateral Cryptorchism

Bilateral Nondescent Testicle

Bilateral Undescended Testes

Bilateral Ectopic Testes
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14858 TNP2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus TNP2 RGD RGD:3885
Mus musculus TNP2 MGD MGI:98785
Bos taurus TNP2 VGNC VGNC:36198
Felis catus TNP2 VGNC VGNC:66430
Macaca mulatta TNP2 VGNC VGNC:78608
Canis familiaris TNP2 VGNC VGNC:82301
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