2. Gene
  3. Ubash3b - ubiquitin associated and SH3 domain containing, B Gene

Ubash3b - ubiquitin associated and SH3 domain containing, B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: p70; STS-1; TULA-2; 2810457I06Rik

基因 ID: 72828 | 基因类型: protein coding

关于 Ubash3b

功能概要

Enables phosphoprotein binding activity and protein tyrosine Phosphatase activity. Involved in regulation of osteoclast differentiation. Acts upstream of or within several processes, including collagen-activated tyrosine kinase receptor signaling pathway; negative regulation of bone resorption; and platelet aggregation. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; incisor; limb; nasal cavity epithelium; and retina. Orthologous to human UBASH3B (ubiquitin associated and SH3 domain containing B). [provided by Alliance of Genome Resources, Apr 2022]

Ubash3b 基因产物(2)

mRNA Protein Name
NM_001357412.1 NP_001344341.1 ubiquitin-associated and SH3 domain-containing protein B isoform 2
NM_176860.6 NP_789830.1 ubiquitin-associated and SH3 domain-containing protein B isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phosphoprotein binding IDA
IDA: 通过直接分析推断
27609517 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
24256567 MGI
enables protein tyrosine phosphatase activity IDA
IDA: 通过直接分析推断
27609517 MGI
enables protein tyrosine phosphatase activity IMP
IMP: 通过突变表型推断
23149425 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within collagen-activated signaling pathway IMP
IMP: 通过突变表型推断
27609517 MGI
acts upstream of or within collagen-activated tyrosine kinase receptor signaling pathway IMP
IMP: 通过突变表型推断
27609517 MGI
acts upstream of or within negative regulation of bone resorption IMP
IMP: 通过突变表型推断
23149425 MGI
acts upstream of or within negative regulation of osteoclast differentiation IMP
IMP: 通过突变表型推断
23149425 MGI
acts upstream of or within negative regulation of platelet aggregation IMP
IMP: 通过突变表型推断
20585042 MGI
acts upstream of or within negative regulation of protein kinase activity IDA
IDA: 通过直接分析推断
27609517 MGI
acts upstream of or within negative regulation of protein kinase activity IMP
IMP: 通过突变表型推断
20585042 MGI
acts upstream of or within negative regulation of signal transduction IMP
IMP: 通过突变表型推断
23149425 MGI
acts upstream of or within peptidyl-tyrosine dephosphorylation IDA
IDA: 通过直接分析推断
27609517 MGI
acts upstream of or within peptidyl-tyrosine dephosphorylation IMP
IMP: 通过突变表型推断
20585042 MGI
acts upstream of or within platelet activation IMP
IMP: 通过突变表型推断
27609517 MGI
acts upstream of or within platelet aggregation IMP
IMP: 通过突变表型推断
27609517 MGI
involved in regulation of osteoclast differentiation IMP
IMP: 通过突变表型推断
23149425 MGI
acts upstream of or within regulation of protein binding IMP
IMP: 通过突变表型推断
27609517 MGI
acts upstream of or within regulation of release of sequestered calcium ion into cytosol IMP
IMP: 通过突变表型推断
20585042 MGI
acts upstream of signal transduction IMP
IMP: 通过突变表型推断
23149425 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ubiquitin-associated and SH3 domain-containing protein B

T-cell ubiquitin ligand 2

cbl-interacting protein p70

suppressor of T-cell receptor signaling 1

tyrosine-protein phosphatase STS1/TULA2

Ubash3b 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属间
Ubash3b Q8BGG7 ZAP70 Homo sapiens P43403
Anti Bait CoIP
24256567
种属间
Ubash3b Q8BGG7 ZAP70 Homo sapiens P43403
Anti Tag CoIP
24256567
种属间
Ubash3b Q8BGG7 ZAP70 Homo sapiens P43403
Pull Down
24256567
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15332 UBASH3B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ubash3b NCBI NCBI:84959
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