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  2. UQCRH - ubiquinol-cytochrome c reductase hinge protein Gene

UQCRH - ubiquinol-cytochrome c reductase hinge protein Gene

中文名称:泛醇-细胞色素 c 还原酶铰链蛋白

种属: Homo sapiens

同用名: QCR6; UQCR8; MC3DN11

基因 ID: 7388 | 基因类型: protein coding

关于 UQCRH

Cytogenetic location: 1p33 Genomic coordinates (GRCh38): 1:46,303,698-46,316,776 (from NCBI)

This gene has 5 transcripts (splice variants), 232 orthologues and 1 paralogue. Ubiquitous expression in heart (RPKM 164.7), colon (RPKM 117.2) and 25 other tissues.

功能概要

预测启用泛醇-细胞色素-c 还原酶活性。预测参与线粒体电子传递,泛醇到细胞色素 c。位于线粒体中。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable ubiquinol-cytochrome-c reductase activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

UQCRH 基因产物(3)

mRNA Protein Name
NM_001297565.2 NP_001284494.1 cytochrome b-c1 complex subunit 6, mitochondrial isoform 2 precursor
NM_001297566.2 NP_001284495.1 cytochrome b-c1 complex subunit 6, mitochondrial isoform 3 precursor
NM_006004.4 NP_005995.2 cytochrome b-c1 complex subunit 6, mitochondrial isoform 1 precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
enables ubiquinol-cytochrome-c reductase activity IMP
IMP: 通过突变表型推断
34750991 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
28844695 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

UQCRH 蛋白结构

UCR_hinge

UCR_hinge: Ubiquinol-cytochrome C reductase hinge protein (27 - 91)

  • 0
  • 91 a.a.
蛋白主名 其他名称

cytochrome b-c1 complex subunit 6, mitochondrial

complex III subunit 6

UQCRH 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
UQCRH P07919 ENTREP3 Homo sapiens Q96H71
Y2H Array
25416956
种属内
UQCRH P07919 RNF24 Homo sapiens Q9Y225
Validated Y2H
25416956
种属内
UQCRH P07919 RNF24 Homo sapiens Q9Y225
Y2H Prey Pooling
25416956
种属内
UQCRH P07919 NDFIP1 Homo sapiens Q9BT67
Validated Y2H
32296183
种属内
UQCRH P07919 NDFIP1 Homo sapiens Q9BT67
Y2H Array
32296183
种属内
UQCRH P07919 NDFIP1 Homo sapiens Q9BT67
Y2H Prey Pooling
32296183
种属内
UQCRH P07919 PRRG1 Homo sapiens O14668
Y2H Array
32296183
种属内
UQCRH P07919 PRRG1 Homo sapiens O14668
Y2H Prey Pooling
32296183
种属内
UQCRH P07919 NDFIP2 Homo sapiens Q9NV92
Y2H Prey Pooling
32296183
种属内
UQCRH P07919 NDFIP2 Homo sapiens Q9NV92
Validated Y2H
32296183
种属内
UQCRH P07919 NDFIP2 Homo sapiens Q9NV92
Y2H Array
32296183
种属内
UQCRH P07919 ARL8A Homo sapiens Q96BM9
Validated Y2H
25416956
种属内
UQCRH P07919 ARL8A Homo sapiens Q96BM9
Validated Y2H
32296183
种属内
UQCRH P07919 ARL8A Homo sapiens Q96BM9
Y2H Array
25416956
种属内
UQCRH P07919 ARL8A Homo sapiens Q96BM9
Y2H Array
32296183
种属内
UQCRH P07919 ARL8A Homo sapiens Q96BM9
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 UQCRH 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71088 UQCRH Protein, Human (GST) P07919 (M1-K91) ≥95%

关联疾病

疾病名称 别名
Fibroosseous Pseudotumor Of Digits

Fibroosseous Digital Pseudotumor

Fibroosseous Pseudotumor Of The Digits

Non-Syndromic X-Linked Intellectual Disability 1

Mrx1

Mrx18

Mrx78

X-Linked Mental Retardation 1/78

X-Linked Mental Retardation 18

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus UQCRH MGD MGI:1913826
Rattus norvegicus UQCRH RGD RGD:1305987