2. Gene
  3. PPP1R3B - protein phosphatase 1 regulatory subunit 3B Gene

PPP1R3B - protein phosphatase 1 regulatory subunit 3B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：蛋白磷酸酶 1 调节亚基 3B

种属: Homo sapiens

同用名: GL; PTG; PPP1R4

基因 ID: 79660 | 基因类型: protein coding

关于 PPP1R3B

Cytogenetic location: 8p23.1 Genomic coordinates (GRCh38): 8:9,136,255-9,151,539 (from NCBI)

This gene has 2 transcripts (splice variants), 1 gene allele, 210 orthologues and 6 paralogues. Broad expression in liver (RPKM 50.1), heart (RPKM 12.4) and 22 other tissues.

功能概要

该基因编码丝氨酸/蛋氨酸磷酸酶、蛋白磷酸酶-1 的催化亚基。编码的蛋白质在肝脏和骨骼肌组织中表达，可能参与调节这些组织中的糖原合成。该基因可能与年轻人的 2 型糖尿病和成年型糖尿病有关。交替剪接导致编码相同蛋白质的多个转录变体。[RefSeq 提供，2011 年 1 月]

This gene encodes the catalytic subunit of the serine/theonine Phosphatase, protein phosphatase-1. The encoded protein is expressed in liver and skeletal muscle tissue and may be involved in regulating glycogen synthesis in these tissues. This gene may be a involved in type 2 diabetes and maturity-onset diabetes of the young. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Jan 2011]

PPP1R3B 基因产物(2)

mRNA Protein Name
NM_001201329.2 NP_001188258.1 protein phosphatase 1 regulatory subunit 3B
NM_024607.4 NP_078883.2 protein phosphatase 1 regulatory subunit 3B
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15231748 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of glycogen catabolic process IDA
IDA: 通过直接分析推断
22225877 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PPP1R3B 蛋白结构

CBM_21

CBM_21: Carbohydrate/starch-binding module (family 21) (128 - 232)

  • 0
  • 100
  • 200
  • 285 a.a.
蛋白主名 其他名称

protein phosphatase 1 regulatory subunit 3B

PP1 subunit R4

关联疾病

疾病名称 别名
Maturity-Onset Diabetes Of The Young

MODY

Maturity Onset Diabetes Mellitus In Young

Mason-Type Diabetes

Mason Type Diabetes

Maturity Onset Diabetes Of The Young

Mody Syndrome

Diabetes Of The Young, Maturity-Onset
Glycogen Storage Disease Vi

Glycogen Storage Disease Type Vi

Hers Disease

GSD6

Gsd Vi

Hepatic Glycogen Phosphorylase Deficiency

Phosphorylase Deficiency Glycogen-Storage Disease Of Liver

Hers' Disease

Glycogen Storage Disease Type 6

Glycogen Storage Disease 6

Gsd Type Vi

Glycogenosis Type Vi

Glycogen Storage Disease, Type Vi

Hepatophosphorylase Deficiency Glycogenosis

Liver Phosphorylase Deficiency Syndrome

Glycogen Storage Disease Due To Liver Glycogen Phosphorylase Deficiency

Gsd Due To Liver Glycogen Phosphorylase Deficiency

Gsd Type 6

Glycogenosis Due To Liver Glycogen Phosphorylase Deficiency

Glycogenosis Type 6

Hepatic Phosphorylase Deficiency

Liver Glycogen Phosphorylase Deficiency

Her

Glycogen Storage Disease Vib

Gsd-Vi

Liver Phosphorylase Deficiency

Storage Disease, Glycogen, Type Vi
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10999 PPP1R3B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus PPP1R3B MGD MGI:2177268
Rattus norvegicus PPP1R3B RGD RGD:621600
Macaca mulatta PPP1R3B VGNC VGNC:104472
Felis catus PPP1R3B VGNC VGNC:107422
Canis familiaris PPP1R3B VGNC VGNC:44897
Bos taurus PPP1R3B VGNC VGNC:33243
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