ICE2 - interactor of little elongation complex ELL subunit 2 Gene

中文名称：小伸长复合体 ELL 亚基 2 的相互作用体

种属: Homo sapiens

同用名: BRCC1; NARG2

关于 ICE2

功能概要

该基因编码小延伸复合体 (LEC) 的蛋白质成分，该复合体在小核 RNA (snRNA) 转录中发挥作用。 LEC 通过增强 RNA 聚合酶 II 的占据和转录延伸来调节 snRNA 转录。编码的蛋白质和其他 LEC 成分已被证明定位于 Cajal 体，这是核糖核蛋白 (RNP) 复合体组装的位点。已在 3 号和 4 号染色体上鉴定出该基因的假基因。[RefSeq 提供，2017 年 5 月]

This gene encodes a protein component of the little elongation complex (LEC), which plays a role in small nuclear RNA (snRNA) transcription. The LEC regulates snRNA transcription by enhancing both RNA Polymerase II occupancy and transcriptional elongation. The encoded protein and Other LEC components have been shown to localize to Cajal bodies, which are sites of ribonucleoprotein (RNP) complex assembly. Pseudogenes of this gene have been identified on chromosomes 3 and 4. [provided by RefSeq, May 2017]