RMI1 - RecQ mediated genome instability 1 Gene

中文名称：RecQ 介导的基因组不稳定性 1

种属: Homo sapiens

同用名: BLAP75; FAAP75; C9orf76

基因 ID: 80010 | 基因类型: protein coding

关于 RMI1

Cytogenetic location: 9q21.32 Genomic coordinates (GRCh38): 9:83,980,359-84,004,074 (from NCBI)

This gene has 2 transcripts (splice variants), 187 orthologues and is associated with 1 phenotype. Ubiquitous expression in testis (RPKM 5.7), lymph node (RPKM 5.0) and 25 other tissues.

功能概要

RMI1 是蛋白质复合物的一个组成部分，它通过双 Holliday 连接的溶解来限制 DNA 交叉形成 (Raynard 等人，2006 [PubMed 16595695]) 。[OMIM 提供，2008 年 3 月]

RMI1 is a component of protein complexes that limit DNA crossover formation via the dissolution of double Holliday junctions (Raynard et al., 2006 [PubMed 16595695]).[supplied by OMIM, Mar 2008]

RMI1 基因产物(5)

mRNA	Protein	Name
NM_001358291.2	NP_001345220.1	recQ-mediated genome instability protein 1
NM_001358292.2	NP_001345221.1	recQ-mediated genome instability protein 1
NM_001358293.2	NP_001345222.1	recQ-mediated genome instability protein 1
NM_001358294.2	NP_001345223.1	recQ-mediated genome instability protein 1
NM_024945.3	NP_079221.2	recQ-mediated genome instability protein 1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	15775963	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in double-strand break repair via homologous recombination	IDA IDA: 通过直接分析推断	23543748	GOA
involved in resolution of DNA recombination intermediates	IDA IDA: 通过直接分析推断	23543748	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
part of RecQ family helicase-topoisomerase III complex	IPI IPI: 通过物理相互作用推断	24984776	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RMI1 蛋白结构

RMI1_N

0
100
200
300
400
500
625 a.a.

蛋白主名

其他名称

recQ-mediated genome instability protein 1

BLM-associated polypeptide, 75 kDa

RMI1 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	RMI1	Q9H9A7	RMI2	Homo sapiens	Q96E14-1	Ion Exchange Chrom	20826341
种属内	RMI1	Q9H9A7	RMI2	Homo sapiens	Q96E14-1	Pull Down	20826342
种属内	RMI1	Q9H9A7	RMI2	Homo sapiens	Q96E14-1	GMS	20826341
种属内	RMI1	Q9H9A7	RMI2	Homo sapiens	Q96E14-1	X-Ray Diffraction	20826342
种属内	RMI1	Q9H9A7	RMI2	Homo sapiens	Q96E14-1	Pull Down	20826341
种属内	RMI1	Q9H9A7	RMI2	Homo sapiens	Q96E14-1	Anti Tag CoIP	20826342
种属内	RMI1	Q9H9A7	RMI2	Homo sapiens	Q96E14-1	GMS	20826342
种属内	RMI1	Q9H9A7	RMI2	Homo sapiens	Q96E14-1	X-Ray Diffraction	20826341
种属内	RMI1	Q9H9A7	RMI2	Homo sapiens	Q96E14	Anti Bait CoIP	20711169
种属内	RMI1	Q9H9A7	TOP3A	Homo sapiens	Q13472	Anti Bait CoIP	20711169
种属内	RMI1	Q9H9A7	TOP3A	Homo sapiens	Q13472	Anti Bait CoIP	15775963
种属内	RMI1	Q9H9A7	TOP3A	Homo sapiens	Q13472	TAP	20360068
种属内	RMI1	Q9H9A7	TOP3A	Homo sapiens	Q13472	Anti Tag CoIP	33961781
种属内	RMI1	Q9H9A7	TOP3A	Homo sapiens	Q13472	Anti Tag CoIP	20826342
种属内	RMI1	Q9H9A7	BLM	Homo sapiens	P54132	IF	15775963
种属内	RMI1	Q9H9A7	BLM	Homo sapiens	P54132	Pull Down	23509288
种属内	RMI1	Q9H9A7	BLM	Homo sapiens	P54132	Anti Bait CoIP	20711169
种属内	RMI1	Q9H9A7	BLM	Homo sapiens	P54132	Anti Bait CoIP	15775963
种属内	RMI1	Q9H9A7	BLM	Homo sapiens	P54132	Anti Tag CoIP	20826342
种属内	RMI1	Q9H9A7	BLM	Homo sapiens	P54132	TAP	20360068

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Bloom Syndrome

BLM	Bs
Bls	Bloom-Torre-Machacek Syndrome
Microcephaly, Growth Restriction, And Increased Sister Chromatid Exchange 1	Mgrisce1
Congenital Telangiectatic Erythema	Congenital Telangiectatic Erythema Syndrome
Growth Deficiency, Sun-Sensitive, Telangiectatic, Hypo And Hyperpigmented Skin, Predisposition To Malignancy And Chromosomal Instability	Bloom'S Syndrome
Bsyn

Baller-Gerold Syndrome

BGS	Craniosynostosis With Radial Defects
Craniosynostosis-Radial Aplasia Syndrome	Craniosynostosis Radial Aplasia Syndrome

Rothmund-Thomson Syndrome, Type 2

Rothmund-Thomson Syndrome	Rts
RTS2	Poikiloderma Of Rothmund-Thomson
Rothmund-Thomson Syndrome Type 2	Congenital Poikiloderma
Poikiloderma Congenitale	Poikiloderma Atrophicans And Cataract
Poikiloderma Congenitale Of Rothmund-Thomson	Poikiloderma Of Rothmund-Thomson Type 2
Rothmund-Thomson Syndrome 2	Erythrokeratodermia Variabilis

Ovarian Mucinous Cystadenocarcinoma

Mucinous Cystadenocarcinoma Of Ovary

Malignant Ovarian Cyst

Rapadilino Syndrome

Absent Thumbs, Dislocated Joints, Long Face With Narrow Palpebral Fissures, Long Slender Nose, Arched Palate	Radial And Patellar Aplasia
Radial And Patellar Hypoplasia	RAPADILINOS

Colorectal Cancer

Colon Cancer	Colorectal Carcinoma
Colon Carcinoma	Colorectal Cancer, Susceptibility To
Carcinoma Of Colon	CRC
Colorectal Cancer With Chromosomal Instability, Somatic	Colon Cancer, Somatic
Colon Cancer, Susceptibility To	Colonic Neoplasms
Colorectal Neoplasms	Colorectal Cancer, Somatic
Colon Cancer, Advanced, Somatic	Colonic Carcinoma
Colorectal Carcinomas	Colon Cancers
Colorectal Cancers	Cancer, Colorectal, Somatic
Cancer, Colon	Cancer, Colorectal, Susceptibility To
Colorectal Neoplasm	Colonic Neoplasm
Malignant Tumor Of Colon

Xeroderma Pigmentosum, Variant Type

Xeroderma Pigmentosum	XPV
Xeroderma Pigmentosum Variant Type	Xeroderma Pigmentosum With Normal Dna Repair Rates
Photosensitivity With Defective Dna Synthesis	Xp
De Sanctis-Cacchione Syndrome	Desanctis-Cacchione Syndrome
Xeroderma Pigmentosa	Xerodermic Idiocy
Xeroderma Pigmentosum Variant	Xp - [Xeroderma Pigmentosum]
Atrophoderma Pigmentosum

Aplastic Anemia

Aplastic Anemia, Susceptibility To	Anemia Aplastic
Idiopathic Aplastic Anemia	Secondary Aplastic Anemia
Idiopathic Bone Marrow Failure	Aplastic Anemia Idiopathic
AA	Anemia, Aplastic
Aplastic Anemia, Idiopathic	Erythroid Aplasia
Aa - [Aplastic Anaemia]	Haematopoietic Aplasia
Aleukia Haemorrhagica	Anaemia Due To Decreased Red Cell Production
Aplasia Bone Marrow	Aplastic Bone Marrow
Hypoplastic Anaemia Nos	Myeloid Bone Marrow Aplasia
Pancytopenia	Panhaematopenia
Hypoproliferative Anaemia	Medullary Hypoplasia
Red Blood Cells Hypoplastic Anaemia	Panmyelophthisis
Panhemocytopenia	Refractive Hypoproliferative Anaemia
Toxic Anaemia	Toxic Aplastic Anaemia
Aplastic Anaemia Due To Toxic Cause	Idiopathic Aplastic Anaemia Nos

Seckel Syndrome

Microcephalic Primordial Dwarfism	Bird-Headed Dwarfism
Harper'S Syndrome	Virchow-Seckel Dwarfism
Nanocephalic Dwarfism	Sckl
Seckel-Type Dwarfism

Fanconi Anemia, Complementation Group A

Fanconi Anemia	Fanconi Pancytopenia
Fanconi Anemia Complementation Group A	FANCA
Fa	Fanconi Panmyelopathy
Fanconi'S Anemia	Fanconi Anaemia
Fanconi'S Anaemia	Fanconi Hypoplastic Anemia
Estren-Dameshek Variant Of Fanconi Anemia	Estren-Dameshek Variant Of Fanconi Pancytopenia
Fanconi Anemia Estren-Dameshek Variant	Fanconis Anemia

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS12014	RMI1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Macaca mulatta	RMI1	VGNC	VGNC:76826
Rattus norvegicus	RMI1	RGD	RGD:1310671
Canis familiaris	RMI1	VGNC	VGNC:45608
Bos taurus	RMI1	VGNC	VGNC:59200
Mus musculus	RMI1	MGD	MGI:1921636
Felis catus	RMI1	VGNC	VGNC:64652

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站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

RMI1 - RecQ mediated genome instability 1 Gene

关于 RMI1

功能概要

RMI1 基因产物(5)

RMI1 蛋白结构

RMI1 蛋白互作信息

关联疾病

直系同源

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RMI1 - RecQ mediated genome instability 1 Gene

关于 RMI1

功能概要

RMI1 基因产物(5)

RMI1 蛋白结构

RMI1 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

X

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