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  2. MLF2 - myeloid leukemia factor 2 Gene

MLF2 - myeloid leukemia factor 2 Gene

中文名称:骨髓性白血病因子 2

种属: Homo sapiens

同用名: NTN4

基因 ID: 8079 | 基因类型: protein coding

关于 MLF2

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:6,747,996-6,753,141 (from NCBI)

This gene has 10 transcripts (splice variants), 205 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 67.7), prostate (RPKM 51.7) and 25 other tissues.

功能概要

预计参与转录调控,以 DNA 为模板。位于膜内。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in regulation of transcription, DNA-templated. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

MLF2 基因产物(3)

mRNA Protein Name
NM_001382225.1 NP_001369154.1 myeloid leukemia factor 2
NM_001382226.1 NP_001369155.1 myeloid leukemia factor 2
NM_005439.3 NP_005430.1 myeloid leukemia factor 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23414517 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

MLF2 蛋白结构

Mlf1IP

Mlf1IP: Myelodysplasia-myeloid leukemia factor 1-interacting protein (26 - 200)

  • 0
  • 100
  • 200
  • 248 a.a.
蛋白主名 其他名称

myeloid leukemia factor 2

myelodysplasia-myeloid leukemia factor 2

MLF2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra MLF2 Q15773 DNAJB6 Homo sapiens O75190
Y2H Fragment Pooling
23414517
Intra MLF2 Q15773 DNAJB6 Homo sapiens O75190
Anti Tag CoIP
25036637
Intra MLF2 Q15773 BAG2 Homo sapiens O95816
Lumier
25036637
Intra MLF2 Q15773 BAG2 Homo sapiens O95816
Anti Tag CoIP
25036637
Intra MLF2 Q15773 BAG2 Homo sapiens O95816
Anti Bait CoIP
17353931
Intra MLF2 Q15773 STUB1 Homo sapiens Q9UNE7
Lumier
25036637
Intra MLF2 Q15773 RAF1 Homo sapiens P04049
Lumier
25036637
Intra MLF2 Q15773 MLF1 Homo sapiens P58340
Lumier
25036637
Intra MLF2 Q15773 HSPB8 Homo sapiens Q9UJY1
Y2H Fragment Pooling
23414517
Intra MLF2 Q15773 BAG3 Homo sapiens O95817
Anti Tag CoIP
25036637
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Myeloid Leukemia

Myeloid Leukaemia

Leukaemia Myelogenous

Leukemia Myelogenous

Myeloid Granulocytic Leukaemia

Myeloid Granulocytic Leukemia

Non-Lymphocytic Leukemia

Leukemia, Myeloid

Granulocytic Leukaemia

Myelogenous Leukaemia

Myeloid Leukaemia, Unspecified, Without Mention Of Remission

Leukemia

Leukemias

Leukaemia, Unspecified, Without Mention Of Remission

Aleukemic Leukaemia

Chronic Leukaemia

Subacute Leukaemia

Leukaemia Disorder

Leukaemia Nos

Fatal Infantile Hypertonic Myofibrillar Myopathy
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus MLF2 RGD RGD:1306294
Mus musculus MLF2 MGD MGI:1353554