2. Gene
  3. ANP32A - acidic nuclear phosphoprotein 32 family member A Gene

ANP32A - acidic nuclear phosphoprotein 32 family member A Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：酸性核磷蛋白 32 家族成员 A

种属: Homo sapiens

同用名: LANP; MAPM; PP32; HPPCn; PHAP1; PHAPI; I1PP2A; C15orf1

基因 ID: 8125 | 基因类型: protein coding

关于 ANP32A

Cytogenetic location: 15q23 Genomic coordinates (GRCh38): 15:68,778,535-68,820,895 (from NCBI)

This gene has 11 transcripts (splice variants), 217 orthologues and 3 paralogues. Ubiquitous expression in lymph node (RPKM 45.8), bone marrow (RPKM 40.5) and 25 other tissues.

功能概要

启用 RNA 结合活性。参与核质运输。位于内质网；核;和细胞质的核周区。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Involved in nucleocytoplasmic transport. Located in endoplasmic reticulum; nucleus; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ANP32A 基因产物(1)

mRNA Protein Name
NM_006305.4 NP_006296.1 acidic leucine-rich nuclear phosphoprotein 32 family member A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16169070 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in nucleocytoplasmic transport IDA
IDA: 通过直接分析推断
11729309 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
11729309 GOA
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
11555662 GOA
located in nucleus IDA
IDA: 通过直接分析推断
11555662 GOA
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
11555662 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ANP32A 蛋白结构

LRR_9

LRR_9: Leucine-rich repeat (49 - 154)

  • 0
  • 100
  • 200
  • 249 a.a.
蛋白主名 其他名称

acidic leucine-rich nuclear phosphoprotein 32 family member A

acidic (leucine-rich) nuclear phosphoprotein 32 family, member A

ANP32A 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ANP32A P39687 E4F1 Homo sapiens Q66K89
Imaging
17557114
种属内
ANP32A P39687 PPP2CA Homo sapiens P67775
Anti Tag CoIP
21806989
种属内
ANP32A P39687 ATXN1 Homo sapiens P54253
Validated Y2H
32814053
种属内
ANP32A P39687 ATXN1 Homo sapiens P54253
Y2H Array
32814053
种属内
ANP32A P39687 ATXN1 Homo sapiens P54253
Y2H Pooling
32814053
种属间
ANP32A P39687 Ppp2ca Rattus norvegicus P63331
Pull Down
21806989
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 ANP32A 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76150 ANP32A Protein, Human (His) P39687 (E2-K238) ≥95%

关联疾病

疾病名称 别名
Spinocerebellar Ataxia 1

Spinocerebellar Ataxia Type 1

SCA1

Olivopontocerebellar Atrophy I

Opca1

Opca4

Menzel Type Opca

Schut-Haymaker Type Opca

Spinocerebellar Atrophy I

Opca I

Olivopontocerebellar Atrophy Iv

Opca Iv

Cerebelloparenchymal Disorder I

Cpd1

Olivopontocerebellar Atrophy 1

Cerebelloparenchymal Disorder 1

Olivopontocerebellar Atrophy 4

Spinocerebellar Atrophy 1

Type 1 Spinocerebellar Ataxia

Spinocerebellar Ataxia-1

Ataxia, Spinocerebellar, Type 1
Influenza

Flu

Influenza With Non-Respiratory Manifestation

Influenza With Other Manifestations

Influenza, Human

Influenza, Susceptibility To

Seasonal Influenza, Virus Identified
Primary Cerebellar Degeneration

Spinocerebellar Degenerations

Cerebellar Degenerations, Primary

Spinocerebellar Degeneration
Avian Influenza

Bird Flu

Influenza In Birds

Avian Flu
Lung Squamous Cell Carcinoma

Squamous Cell Carcinoma Of Lung

Squamous Cell Lung Carcinoma

Epidermoid Cell Carcinoma Of The Lung

Squamous Cell Lung Cancer
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00751 ANP32A Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ANP32A RGD RGD:11508551
Mus musculus ANP32A MGD MGI:108447
Macaca mulatta ANP32A VGNC VGNC:84302
Others ANP32A NCBI
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