RND2 - Rho family GTPase 2 Gene

中文名称：Rho 家族 GTPase 2

种属: Homo sapiens

同用名: ARHN; RHO7; RhoN

关于 RND2

功能概要

该基因编码 Rho GTPase 家族的一个成员，其成员在响应细胞外生长因子的肌动蛋白细胞骨架组织调节中发挥关键作用。这个特殊的家族成员与神经元形态和内体运输的调节有关。该基因定位于 17 号染色体，是乳腺癌-卵巢癌易感基因 BRCA1 的着丝粒邻居。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin Cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian Cancer susceptibility gene BRCA1. [provided by RefSeq, Jul 2008]