2. Gene
  3. ROPN1L - rhophilin associated tail protein 1 like Gene

ROPN1L - rhophilin associated tail protein 1 like Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：rhophilin 相关尾蛋白 1 样

种属: Homo sapiens

同用名: ASP; RSPH11

基因 ID: 83853 | 基因类型: protein coding

关于 ROPN1L

Cytogenetic location: 5p15.2 Genomic coordinates (GRCh38): 5:10,441,879-10,482,807 (from NCBI)

This gene has 5 transcripts (splice variants), 188 orthologues and 2 paralogues. Restricted expression toward testis (RPKM 83.7).

功能概要

该基因编码 ropporin 家族的一个成员。编码的蛋白质存在于精子中，并通过 AKAP3 的两亲性螺旋区域与 A 激酶锚定蛋白 AKAP3 相互作用。已发现该基因的可变剪接转录物变体。[RefSeq 提供，2014 年 10 月]

This gene encodes a member of the ropporin family. The encoded protein is present in sperm and interacts with A-kinase anchoring protein, AKAP3, through the amphipathic helix region of AKAP3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2014]

ROPN1L 基因产物(2)

mRNA Protein Name
NM_001201466.2 NP_001188395.1 ropporin-1-like protein
NM_031916.5 NP_114122.2 ropporin-1-like protein
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
18421703 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cilium IDA
IDA: 通过直接分析推断
27120127 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
18421703 GOA
located in motile cilium IDA
IDA: 通过直接分析推断
18421703 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ropporin-1-like protein

AKAP-associated sperm protein

ROPN1L 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ROPN1L Q96C74 SPA17 Homo sapiens Q15506
Anti Tag CoIP
28514442
种属内
ROPN1L Q96C74 SPA17 Homo sapiens Q15506
Anti Tag CoIP
33961781
种属内
ROPN1L Q96C74 RSPH3 Homo sapiens Q86UC2
Y2H Array
31515488
种属内
ROPN1L Q96C74 RSPH3 Homo sapiens Q86UC2
Y2H Array
32296183
种属内
ROPN1L Q96C74 RSPH3 Homo sapiens Q86UC2
Y2H Prey Pooling
32296183
种属内
ROPN1L Q96C74 BEX2 Homo sapiens Q9BXY8
Validated Y2H
32296183
种属内
ROPN1L Q96C74 ROPN1L Homo sapiens Q96C74
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Opisthorchiasis

Infection By Opisthorchis

Infection Due To Opisthorchis

Infection Due To Cat Liver Fluke

Infection By Cat Liver Fluke

Opisthorchiosis

Cat Liver Fluke Fever

Cat Liver Fluke Disease

Opisthorchis Infestation

Cat Liver Fluke Infestation
Primary Ciliary Dyskinesia

Immotile Cilia Syndrome

Kartagener Syndrome

Dextrocardia Bronchiectasis And Sinusitis

Pcd

Ciliary Motility Disorders

Ciliary Motility Disorder

Immotile Ciliary Syndrome

Ciliary Dyskinesia Primary

Ics

Polynesian Bronchiectasis

Dextrocardia-Bronchiectasis-Sinusitis Syndrome

Immotile Cilia Syndrome, Kartagener Type

Primary Ciliary Dyskinesia And Situs Inversus

Primary Ciliary Dyskinesia, Kartagener Type

Siewert Syndrome

Dyskinesia, Ciliary, Primary
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12123 ROPN1L Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus ROPN1L VGNC VGNC:34086
Rattus norvegicus ROPN1L RGD RGD:1591367
Mus musculus ROPN1L MGD MGI:2182357
Canis familiaris ROPN1L VGNC VGNC:45692
Macaca mulatta ROPN1L VGNC VGNC:110437
Felis catus ROPN1L VGNC VGNC:64718
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