2. Gene
  3. Sucnr1 - succinate receptor 1 Gene

Sucnr1 - succinate receptor 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：琥珀酸受体 1

种属: Mus musculus

同用名: Gpr91

基因 ID: 84112 | 基因类型: protein coding

关于 Sucnr1

Chromosome 3: 59,989,290-59,994,987 forward strand.GRCm39:CM000996.3

This gene has 2 transcripts (splice variants), 211 orthologues, 13 paralogues and is associated with 8 phenotypes. Biased expression in subcutaneous fat pad adult (RPKM 18.1), genital fat pad adult (RPKM 15.8) and 3 other tissues.

功能概要

该基因编码的蛋白可启动信号受体活动。在几个过程的上游或内部起作用，包括参与免疫反应的巨噬细胞激活；调节血管紧张素代谢过程；和肾素分泌到血液中。预测位于细胞表面。在神经视网膜和视网膜中表达。与人类 SUCNR1（琥珀酸受体 1）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables signaling receptor activity. Acts upstream of or within several processes, including macrophage activation involved in immune response; regulation of angiotensin metabolic process; and Renin secretion into blood stream. Predicted to be located in cell surface. Is expressed in neural retina and retina. Orthologous to human SUCNR1 (Succinate Receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Sucnr1 基因产物(2)

mRNA Protein Name
NM_032400.2 NP_115776.2 succinate receptor 1
NM_032400.2 NP_115776.2 succinate receptor 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor activity IDA
IDA: 通过直接分析推断
18820681 MGI
enables signaling receptor activity IDA
IDA: 通过直接分析推断
27481132 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
18820681 MGI
involved in energy homeostasis IDA
IDA: 通过直接分析推断
36977414 MGI
acts upstream of or within glucose homeostasis IMP
IMP: 通过突变表型推断
28382382 MGI
acts upstream of or within interleukin-1 beta production IMP
IMP: 通过突变表型推断
27481132 MGI
acts upstream of or within macrophage activation involved in immune response IMP
IMP: 通过突变表型推断
27481132 MGI
acts upstream of or within macrophage cytokine production IMP
IMP: 通过突变表型推断
27481132 MGI
acts upstream of or within positive regulation of chemotaxis IMP
IMP: 通过突变表型推断
28382382 MGI
acts upstream of or within positive regulation of inflammatory response IMP
IMP: 通过突变表型推断
28382382 MGI
acts upstream of or within regulation of angiotensin metabolic process IMP
IMP: 通过突变表型推断
18535668 MGI
acts upstream of or within renin secretion into blood stream IMP
IMP: 通过突变表型推断
18535668 MGI
acts upstream of or within response to calcium ion IMP
IMP: 通过突变表型推断
18535668 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Sucnr1 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (19 - 300)

7tm_GPCRs

7tm_GPCRs: cd14964 (21 - 45)

7tm_GPCRs

7tm_GPCRs: cd14964 (54 - 75)

7tm_GPCRs

7tm_GPCRs: cd14964 (91 - 113)

7tm_GPCRs

7tm_GPCRs: cd14964 (136 - 152)

7tm_GPCRs

7tm_GPCRs: cd14964 (180 - 203)

7tm_GPCRs

7tm_GPCRs: cd14964 (226 - 248)

7tm_GPCRs

7tm_GPCRs: cd14964 (268 - 293)

  • 0
  • 100
  • 200
  • 317 a.a.
蛋白主名 其他名称

succinate receptor 1

G protein-coupled receptor 91

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-130246 NF-56-EJ40 99.92% 否
HY-125791 cis-Epoxysuccinic acid Agonist 99.00% 否
HY-154946 SUCNR1-IN-1 Inhibitor 99.33% 否
HY-RS14004 Sucnr1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-156955 SUCNR1-IN-2 99.74% 否
HY-130246A NF-56-EJ40 hydrochloride / 否
HY-RS14003 SUCNR1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS14005 Sucnr1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sucnr1 NCBI NCBI:56670
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z