2. Gene
  3. UBL7 - ubiquitin like 7 Gene

UBL7 - ubiquitin like 7 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：泛素样 7

种属: Homo sapiens

同用名: TCBA1; BMSC-UbP

基因 ID: 84993 | 基因类型: protein coding

关于 UBL7

Cytogenetic location: 15q24.1 Genomic coordinates (GRCh38): 15:74,445,977-74,461,188 (from NCBI)

This gene has 9 transcripts (splice variants), 1 gene allele, 223 orthologues and 5 paralogues. Ubiquitous expression in testis (RPKM 17.2), brain (RPKM 14.5) and 25 other tissues.

功能概要

预测可启用多聚泛素修饰依赖性蛋白结合活性。预计参与泛素依赖性蛋白质分解代谢过程。预计在胞质溶胶中有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable polyubiquitin modification-dependent protein binding activity. Predicted to be involved in ubiquitin-dependent protein catabolic process. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

UBL7 基因产物(6)

mRNA Protein Name
NM_001286739.2 NP_001273668.1 ubiquitin-like protein 7 isoform a
NM_001286740.1 NP_001273669.1 ubiquitin-like protein 7 isoform a
NM_001286741.2 NP_001273670.1 ubiquitin-like protein 7 isoform b
NM_001286742.2 NP_001273671.1 ubiquitin-like protein 7 isoform b
NM_032907.5 NP_116296.1 ubiquitin-like protein 7 isoform a
NM_201265.2 NP_957717.1 ubiquitin-like protein 7 isoform a
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables molecular adaptor activity IDA
IDA: 通过直接分析推断
36943869 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cytoplasm IDA
IDA: 通过直接分析推断
36943869 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

UBL7 蛋白结构

ubiquitin

ubiquitin: Ubiquitin family (40 - 92)

UBA

UBA: UBA/TS-N domain (340 - 373)

  • 0
  • 100
  • 200
  • 300
  • 380 a.a.
蛋白主名 其他名称

ubiquitin-like protein 7

ubiquitin-like 7 (bone marrow stromal cell-derived)

UBL7 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
UBL7 Q96S82 AP1G1 Homo sapiens O43747-2
Y2H Prey Pooling
25416956
种属内
UBL7 Q96S82 AP1G1 Homo sapiens O43747-2
Y2H Array
25416956
种属内
UBL7 Q96S82 CAPN7 Homo sapiens Q7Z479
Y2H Array
25416956
种属内
UBL7 Q96S82 CAPN7 Homo sapiens Q7Z479
Y2H Prey Pooling
25416956
种属内
UBL7 Q96S82 UBE4B Homo sapiens O95155
Anti Tag CoIP
33961781
种属内
UBL7 Q96S82 VBP1 Homo sapiens P61758
Y2H Array
25416956
种属内
UBL7 Q96S82 ERCC1 Homo sapiens P07992
Y2H Prey Pooling
25416956
种属内
UBL7 Q96S82 ERCC1 Homo sapiens P07992
Validated Y2H
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Phlyctenulosis

Phlyctenular Keratoconjunctivitis

Strumous Ophthalmia
Chromosome 15q24 Deletion Syndrome

15q24 Microdeletion Syndrome

Del(15)(Q24)

Monosomy 15q24

15q24 Microdeletion

15q24 Deletion

Interstitial Deletion Of Chromosome 15q24
Arteritic Anterior Ischemic Optic Neuropathy
Severe Nonproliferative Diabetic Retinopathy

High Risk Non Proliferative Diabetic Retinopathy

Severe Npdr
Background Diabetic Retinopathy

Non Proliferative Diabetic Retinopathy

Non-Proliferative Diabetic Retinopathy

Nonproliferative Diabetic Retinopathy
Retinal Microaneurysm

Microaneurysm
Chronic Intestinal Vascular Insufficiency

Chronic Mesenteric Ischemia

Cmi - Chronic Mesenteric Ischaemia
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15377 UBL7 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus UBL7 VGNC VGNC:50128
Felis catus UBL7 VGNC VGNC:66776
Rattus norvegicus UBL7 RGD RGD:1303055
Mus musculus UBL7 MGD MGI:1916709
Macaca mulatta UBL7 VGNC VGNC:82267
Canis familiaris UBL7 VGNC VGNC:48079
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