CLIC3 - chloride intracellular channel 3 Gene

中文名称：氯离子细胞内通道 3

种属: Homo sapiens

关于 CLIC3

功能概要

氯离子通道是一组不同的蛋白质，可调节基本细胞过程，包括稳定细胞膜电位、跨上皮转运、维持细胞内 pH 值和调节细胞体积。氯离子胞内通道 3 是 p64 家族的成员，主要位于细胞核中并刺激氯离子通道活性。此外，该蛋白可能参与细胞生长控制，基于其与 MAP 激酶家族成员 ERK7 的关联。[RefSeq 提供，2008 年 7 月]

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family. [provided by RefSeq, Jul 2008]