USP10 - ubiquitin specific peptidase 10 Gene

中文名称：泛素特异性肽酶 10

种属: Homo sapiens

同用名: UBPO

关于 USP10

功能概要

泛素是一种高度保守的蛋白质，与其他蛋白质共价连接以调节它们的功能和降解。该基因编码半胱氨酸蛋白酶泛素特异性蛋白酶家族的成员。该酶特异性地从泛素缀合的蛋白质底物上切割泛素。该蛋白质存在于细胞核和细胞质中。它作为 DNA 结合的雄激素受体复合物的辅助因子发挥作用，并被 Ras-GTPase 途径中的一种蛋白质抑制。人类基因组包含几个与该基因相似的假基因。已经发现了该基因的几种转录变体，一些是蛋白质编码的，另一些不是蛋白质编码的。[RefSeq 提供，2013 年 1 月]

Ubiquitin is a highly conserved protein that is covalently linked to Other proteins to regulate their function and degradation. This gene encodes a member of the Ubiquitin-Specific Protease family of cysteine proteases. The Enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound Androgen Receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and Others not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2013]