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  2. RAB33A - RAB33A, member RAS oncogene family Gene

RAB33A - RAB33A, member RAS oncogene family Gene

中文名称:RAB33A,成员 RAS 致癌基因家族

种属: Homo sapiens

同用名: RabS10

基因 ID: 9363 | 基因类型: protein coding

关于 RAB33A

Cytogenetic location: Xq26.1 Genomic coordinates (GRCh38): X:130,110,623-130,184,870 (from NCBI)

This gene has 1 transcript (splice variant), 183 orthologues and 68 paralogues. Biased expression in brain (RPKM 10.9), lymph node (RPKM 3.6) and 7 other tissues.

功能概要

该基因编码的蛋白质属于小 GTPase 超家族 Rab 家族。它是 GTP 结合蛋白,可能参与囊泡运输。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is GTP-binding protein and may be involved in vesicle transport. [provided by RefSeq, Jul 2008]

RAB33A 基因产物(1)

mRNA Protein Name
NM_004794.3 NP_004785.1 ras-related protein Rab-33A
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16189514 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in antigen processing and presentation IMP
IMP: 通过突变表型推断
19717423 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

RAB33A 蛋白结构

Ras

Ras: Ras family (38 - 200)

  • 0
  • 100
  • 200
  • 237 a.a.
蛋白主名 其他名称

ras-related protein Rab-33A

Small GTP-binding protein S10

RAB33A 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
RAB33A Q14088 KRT34 Homo sapiens O76011
Y2H Prey Pooling
32296183
种属内
RAB33A Q14088 KRT34 Homo sapiens O76011
Y2H Array
32296183
种属内
RAB33A Q14088 LRP2BP Homo sapiens Q9P2M1
Y2H Array
32296183
种属内
RAB33A Q14088 LRP2BP Homo sapiens Q9P2M1
Y2H Prey Pooling
32296183
种属内
RAB33A Q14088 LRP2BP Homo sapiens Q9P2M1
Validated Y2H
32296183
种属内
RAB33A Q14088 RUFY2 Homo sapiens Q8WXA3-4
Validated Y2H
32296183
种属内
RAB33A Q14088 RUFY2 Homo sapiens Q8WXA3-4
Y2H Prey Pooling
32296183
种属内
RAB33A Q14088 RUFY2 Homo sapiens Q8WXA3-4
Y2H Array
32296183
种属内
RAB33A Q14088 ATG16L1 Homo sapiens Q676U5
Anti Tag CoIP
33961781
种属内
RAB33A Q14088 ATG16L1 Homo sapiens Q676U5
Y2H Prey Pooling
32296183
种属内
RAB33A Q14088 ATG16L1 Homo sapiens Q676U5
Validated Y2H
32296183
种属内
RAB33A Q14088 ATG16L1 Homo sapiens Q676U5
Y2H Array
32296183
种属内
RAB33A Q14088 RABAC1 Homo sapiens Q9UI14
Y2H Array
19060904
种属内
RAB33A Q14088 RABAC1 Homo sapiens Q9UI14
Y2H Pooling
19060904
种属内
RAB33A Q14088 RABAC1 Homo sapiens Q9UI14
Y2H Pooling
16189514
种属内
RAB33A Q14088 ARL6IP1 Homo sapiens Q15041
Y2H Prey Pooling
25416956
种属内
RAB33A Q14088 RUFY3 Homo sapiens Q7L099
Y2H Array
32296183
种属内
RAB33A Q14088 RUFY3 Homo sapiens Q7L099
Y2H Prey Pooling
32296183
种属内
RAB33A Q14088 RUFY3 Homo sapiens Q7L099
Validated Y2H
32296183
种属内
RAB33A Q14088 LNX1 Homo sapiens Q8TBB1
Validated Y2H
32296183
种属内
RAB33A Q14088 LNX1 Homo sapiens Q8TBB1
Y2H Prey Pooling
32296183
种属内
RAB33A Q14088 LNX1 Homo sapiens Q8TBB1
Y2H Array
32296183
种属内
RAB33A Q14088 SIAH1 Homo sapiens Q8IUQ4
Y2H Prey Pooling
25416956
种属内
RAB33A Q14088 SIAH1 Homo sapiens Q8IUQ4
Validated Y2H
25416956
种属内
RAB33A Q14088 PSMF1 Homo sapiens Q92530
Y2H Prey Pooling
32296183
种属内
RAB33A Q14088 PSMF1 Homo sapiens Q92530
Validated Y2H
32296183
种属内
RAB33A Q14088 PSMF1 Homo sapiens Q92530
Y2H Array
32296183
种属内
RAB33A Q14088 KRT31 Homo sapiens Q15323
Validated Y2H
32296183
种属内
RAB33A Q14088 KRT31 Homo sapiens Q15323
Y2H Prey Pooling
32296183
种属内
RAB33A Q14088 KRT31 Homo sapiens Q15323
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Combined Oxidative Phosphorylation Deficiency
Spondyloepimetaphyseal Dysplasia, X-Linked, With Hypomyelinating Leukodystrophy

SEMDHL

Leukoencephalopathy With Metaphyseal Chondrodysplasia

H-Smd

Leukoencephalopathy-Metaphyseal Chondrodysplasia Syndrome

Lkmcd

Semd, X-Linked, With Mental Deterioration

Leukoencephalopathy-Spondylometaphyseal Dysplasia Syndrome

Hypomyelination-Spondylometaphyseal Dysplasia Syndrome

X-Linked Spondyloepimetaphyseal Dysplasia With Hypomyelinating Leukodystrophy

Leukoencephalopathy-Spondyloepimetaphyseal Dysplasia Syndrome

Hypomyelination-Spondyloepimetaphyseal Dysplasia Syndrome

Leukoencephalopathy-Semd Syndrome

Semd X-Linked With Mental Deterioration

Deafness, X-Linked 5, With Peripheral Neuropathy

Deafness, X-Linked 5

DFNX5

Aunx1

Auditory Neuropathy, X-Linked, 1, With Peripheral Sensory Neuropathy

X-Linked Deafness 5

X-Linked Auditory Neuropathy With Peripheral Sensory Neuropathy Type 1

X-Linked Hsan With Deafness

X-Linked Auditory Neuropathy 1 With Peripheral Sensory Neuropathy

X-Linked Hereditary Sensory And Autonomic Neuropathy With Deafness

X-Linked Hsan With Hearing Loss

X-Linked Hereditary Sensory And Autonomic Neuropathy With Hearing Loss

Deafness, X-Linked, 5, With Peripheral Neuropathy

Deafness, X-Linked, Type 5

Combined Oxidative Phosphorylation Deficiency 6

Severe X-Linked Mitochondrial Encephalomyopathy

COXPD6

Mitochondrial Encephalomyopathy Due To Combined Oxidative Phosphorylation Defect 6

Mitochondrial Encephalomyopathy Due To Coxpd6

Encephalomyopathy, Mitochondrial, X-Linked

Encephalomyopathy Mitochondrial X-Linked

Oxidative Phosphorylation Deficiency, Combined, Type 6

Charcot-Marie-Tooth Disease X-Linked Recessive 4

Cmt4x

Cmtx4

Cowchock Syndrome

X-Linked Charcot-Marie-Tooth Disease Type 4

Axonal Motor Sensory Neuropathy With Deafness And Mental Retardation

Charcot-Marie-Tooth Disease With Deafness And Mental Retardation

Nadmr

Namsd

Charcot-Marie-Tooth Disease, X-Linked Recessive, 4, With Or Without Cerebellar Ataxia

Cowchock Syndrome

CMTX4

Cowck

Neuropathy, Axonal Motor-Sensory, With Deafness And Mental Retardation

Namsd

Nadmr

Charcot-Marie-Tooth Disease With Deafness And Mental Retardation

Charcot-Marie-Tooth Disease Deafness Mental Retardation

Charcot-Marie-Tooth Disease X-Linked Recessive 4

Hypomyelinating Leukodystrophy

Hld

Leukodystrophy, Hypomyelinating

Leukodystrophy

Leukodystrophies

Sensorineural Hearing Loss

Sensory Hearing Loss

Sensorineural Deafness

Sensorineural Hearing Loss Disorder

Hearing Loss, Sensorineural

Central Hearing Loss

High Frequency Deafness

High Frequency Hearing Loss

High-Frequency Hearing Loss

Perceptive Deafness

Perceptive Hearing Loss

Perceptive Hearing Loss Or Deafness

Hearing Loss Sensorineural

Deafness Sensorineural

Hearing Loss High-Frequency

Hearing Loss, Central

Hearing Loss, High-Frequency

Developmental And Epileptic Encephalopathy 33

DEE33

Epileptic Encephalopathy, Early Infantile, 33

Eiee33

Developmental And Epileptic Encephalopathy, 33

Early Infantile Epileptic Encephalopathy 33

Encephalopathy, Epileptic, Early Infantile, Type 33

Prostate Transitional Cell Carcinoma

Transitional Cell Carcinoma Of Prostate

Primary Prostate Urothelial Carcinoma

Dyggve-Melchior-Clausen Disease

Dyggve-Melchior-Clausen Syndrome

DMC

Dmc Disease

Pseudo-Morquio Disease Type I

Dmc Syndrome

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris RAB33A VGNC VGNC:45275
Rattus norvegicus RAB33A RGD RGD:1563280
Bos taurus RAB33A VGNC VGNC:33642
Mus musculus RAB33A MGD MGI:109493