2. Gene
  3. FAM20B - FAM20B glycosaminoglycan xylosylkinase Gene

FAM20B - FAM20B glycosaminoglycan xylosylkinase Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：FAM20B 糖胺聚糖木糖激酶

种属: Homo sapiens

同用名: gxk1

基因 ID: 9917 | 基因类型: protein coding

关于 FAM20B

Cytogenetic location: 1q25.2 Genomic coordinates (GRCh38): 1:179,017,334-179,076,567 (from NCBI)

This gene has 2 transcripts (splice variants), 207 orthologues and 2 paralogues. Ubiquitous expression in adrenal (RPKM 13.7), brain (RPKM 12.6) and 25 other tissues.

功能概要

启用磷酸转移酶活性，醇基作为受体。预测参与蛋白多糖的生物合成过程。位于高尔基体和核质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables phosphotransferase activity, alcohol group as acceptor. Predicted to be involved in proteoglycan biosynthetic process. Located in Golgi apparatus and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

FAM20B 基因产物(3)

mRNA Protein Name
NM_001324310.2 NP_001311239.1 glycosaminoglycan xylosylkinase
NM_001324311.2 NP_001311240.1 glycosaminoglycan xylosylkinase
NM_014864.4 NP_055679.1 glycosaminoglycan xylosylkinase
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phosphotransferase activity, alcohol group as acceptor IDA
IDA: 通过直接分析推断
19473117 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25331875 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
19473117 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

FAM20B 蛋白结构

Fam20C

Fam20C: Golgi casein kinase, C-terminal, Fam20 (190 - 402)

  • 0
  • 100
  • 200
  • 300
  • 409 a.a.
蛋白主名 其他名称

glycosaminoglycan xylosylkinase

family with sequence similarity 20, member B

FAM20B 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
FAM20B O75063 BSCL2 Homo sapiens J3KQ12
Y2H Prey Pooling
32296183
种属内
FAM20B O75063 BSCL2 Homo sapiens J3KQ12
Y2H Array
32296183
种属内
FAM20B O75063 TMEM80 Homo sapiens Q96HE8
Y2H Prey Pooling
32296183
种属内
FAM20B O75063 TMEM80 Homo sapiens Q96HE8
Validated Y2H
32296183
种属内
FAM20B O75063 TMEM80 Homo sapiens Q96HE8
Y2H Array
32296183
种属内
FAM20B O75063 KCNJ6 Homo sapiens P48051
Validated Y2H
32296183
种属内
FAM20B O75063 KCNJ6 Homo sapiens P48051
Y2H Array
32296183
种属内
FAM20B O75063 KCNJ6 Homo sapiens P48051
Y2H Prey Pooling
32296183
种属内
FAM20B O75063 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
种属内
FAM20B O75063 GPR152 Homo sapiens Q8TDT2
Validated Y2H
32296183
种属内
FAM20B O75063 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
种属内
FAM20B O75063 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
种属内
FAM20B O75063 FAM209A Homo sapiens Q5JX71
Validated Y2H
32296183
种属内
FAM20B O75063 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
种属内
FAM20B O75063 ASPHD2 Homo sapiens Q6ICH7
Anti Tag CoIP
33961781
种属内
FAM20B O75063 ASPHD2 Homo sapiens Q6ICH7
Anti Tag CoIP
28514442
种属内
FAM20B O75063 FFAR2 Homo sapiens O15552
Y2H Prey Pooling
32296183
种属内
FAM20B O75063 FFAR2 Homo sapiens O15552
Y2H Array
32296183
种属内
FAM20B O75063 SLC7A14 Homo sapiens Q8TBB6
Y2H Prey Pooling
32296183
种属内
FAM20B O75063 SLC7A14 Homo sapiens Q8TBB6
Validated Y2H
32296183
种属内
FAM20B O75063 SLC7A14 Homo sapiens Q8TBB6
Y2H Array
32296183
种属内
FAM20B O75063 TIMMDC1 Homo sapiens Q9NPL8
Validated Y2H
32296183
种属内
FAM20B O75063 TIMMDC1 Homo sapiens Q9NPL8
Y2H Prey Pooling
32296183
种属内
FAM20B O75063 TIMMDC1 Homo sapiens Q9NPL8
Y2H Array
32296183
种属内
FAM20B O75063 DCN Homo sapiens P07585
Phosphotransferase
25331875
种属内
FAM20B O75063 DCN Homo sapiens P07585
Protein Kinase Assay
25789606
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 FAM20B 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76326 FAM20B Protein, Human (HEK293, Fc) O75063/NP_055679.1 (S31-L409) ≥95%

关联疾病

疾病名称 别名
Desbuquois Dysplasia

Desbuquois Syndrome

Micromelic Dwarfism With Vertebral And Metaphyseal Abnormalities And Advanced Carpotarsal Ossification

Dysplasia, Desbuquois
Gingival Fibromatosis

Hereditary Gingival Fibromatosis

Hereditary Gingival Hyperplasia

Autosomal Dominant Gingival Fibromatosis

Autosomal Dominant Gingival Hyperplasia

Fibromatosis, Gingival, Hereditary

Fibromatosis, Gingival
Spondyloepiphyseal Dysplasia With Congenital Joint Dislocations

Spondyloepiphyseal Dysplasia

Chst3-Related Skeletal Dysplasia

Humerospinal Dysostosis

Spondyloepiphyseal Dysplasia, Omani Type

Chondrodysplasia With Multiple Dislocations

SEDCJD

Hsd

Cdmd

Humero-Spinal Dysostosis

Kozlowski Celermajer Tink Syndrome

Chondrodysplasia With Congenital Joint Dislocations, Chst3 Type

Larsen Syndrome, Recessive Type

Humero-Spinal Dysostosis With Congenital Heart Disease

Omani Type

Sed

Chst3 Deficiency

Chst3-Related Dysplasia

Recessive Larsen Syndrome

Autosomal Recessive Larsen Syndrome

Sed With Luxations, Chst3 Type

Sed, Omani Type

Sdcd, Chst3 Type

Spondyloepiphyseal Dysplasia With Congenital Joint Dyslocations, Chst3 Type

Sed Omani Type

Spondyloepiphyseal Dysplasia Omani Type

Larsen Syndrome, Autosomal Recessive

Mucopolysaccharidosis Iv

Spondyloepiphyseal Dysplasia, Congenita
Temtamy Preaxial Brachydactyly Syndrome

Preaxial Brachydactyly Syndrome, Temtamy Type

TPBS

Intellectual Disability Syndrome With Preaxial Brachydactyly, Hyperphalangism, Deafness And Orodental Anomalies

Preaxial Brachydactyly Syndrome Temtamy Type
Hereditary Multiple Exostoses

Multiple Congenital Exostosis

Hereditary Multiple Exostoses 1

Hereditary Multiple Exostoses 2

Hereditary Multiple Exostoses 3

Multiple Exostosis Syndromes

Multiple Ostechondromas

Osteochondromatosis Syndrome

Exostoses Multiple Hereditary

Exostoses, Multiple Hereditary
Exostosis

Osteophyte

Exostoses

Orbital Exostosis

Exostosis Of Orbit

Bone Spur

Bony Outgrowth

Swimmer'S Exostosis

Osteophytes

External Exotoses

Cartilaginous Exostosis
Spondyloepimetaphyseal Dysplasia With Joint Laxity

Dysplasia, Spondyloepimetaphyseal, With Joint Laxity

Semdjl

Spondyloepimetaphyseal Dysplasia Joint Laxity

Semd-Jl

Semdjl1

Spondyloepimetaphyseal Dysplasia With Joint Laxity Type 1

Spondyloepimetaphyseal Dysplasia With Joint Laxity, Beighton Type
Amelogenesis Imperfecta

Ai

Congenital Enamel Hypoplasia

Al - [Amelogenesis Imperfecta]
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04705 FAM20B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus FAM20B VGNC VGNC:28786
Felis catus FAM20B VGNC VGNC:62098
Mus musculus FAM20B MGD MGI:2443990
Canis familiaris FAM20B VGNC VGNC:40655
Rattus norvegicus FAM20B RGD RGD:1311162
Macaca mulatta FAM20B VGNC VGNC:72317
Others FAM20B NCBI
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