2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. Inetetamab

Inetetamab  (Synonyms: 伊尼妥单抗)

目录号: HY-P99969 纯度: 96.54%
COA

摩尔计算器

Inetetamab 是一种结合 HER2 受体 结构域 IV 的单克隆抗体。Inetetamab 单独使用或与酪氨酸激酶抑制剂一起使用时具有抗肿瘤活性。

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Inetetamab Chemical Structure

Inetetamab Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥3500
In-stock
5 mg ￥9100
In-stock
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50 mg   询价  

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Customer Review

Inetetamab 相关抗体

Top Publications Citing Use of Products

查看 EGFR 亚型特异性产品:

查看所有亚型
EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Inetetamab is a monoclonal antibody binding to domain IV of HER2 receptor. Inetetamab alone or together with tyrosine kinase inhibitors has antitumor activities[1][2].

种属

Humanized

IC50 & Target[1]

HER2

 

体内研究
(In Vivo)

Inetetamab (20 mg/kg，腹腔注射) 在 JIMT-1 异种移植小鼠模型中显示出抗肿瘤作用[2]。
Inetetamab (20 mg/kg, 腹腔注射) 与 Pyrotinib 或 Cyclophosphamide 一起在 JIMT-1 和 NCI-N87 异种移植小鼠模型中也具有明显的抗肿瘤作用[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: JIMT-1 xenograft mouse model[2]
Dosage: 20 mg/kg, or together with Pyrotinib (20 mg/kg, p.o.) or Cyclophosphamide (10 mg/kg, p.o.)
Administration: i.p, twice a week
Result: Inhibited tumor growth with a tumor growth inhibition (TGI) rate of approximately 40%, and induces a stronger synergistic antitumor effect with Pyrotinib or Cyclophosphamide.
Clinical Trial
性状

液体

颜色

Colorless to light yellow

中文名称

伊尼妥单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: 96.54%

COA (150 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Inetetamab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Inetetamab伊尼妥单抗EGFREpidermal growth factor receptorErbB-1HER1Cancerbreast cancergastric cancerJIMT-1NCI-N87monoclonal antibodyInhibitorinhibitorinhibit

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