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  4. JNJ-7925476 hydrochloride

JNJ-7925476 (hydrochloride) 是一种三重单胺摄取抑制剂，具有调节神经递质水平和抗抑郁活性。JNJ-7925476 (hydrochloride)在大鼠体内可快速吸收进入血浆，在脑内浓度高于血浆，可诱导大鼠大脑皮层细胞外血清素、多巴胺和去甲肾上腺素水平升高，在小鼠悬尾实验中表现出抗抑郁活性。

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JNJ-7925476 hydrochloride Chemical Structure

JNJ-7925476 hydrochloride Chemical Structure

CAS No. : 109085-56-5

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JNJ-7925476 hydrochloride 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

JNJ-7925476 (hydrochloride) is a triple monoamine uptake inhibitor with the ability to regulate neurotransmitter levels and antidepressant activity. JNJ-7925476 (hydrochloride) can be rapidly absorbed into the plasma in rats, with a higher concentration in the brain than in plasma. It can induce an increase in the levels of extracellular serotonin, dopamine, and norepinephrine in the rat cerebral cortex, and exhibits antidepressant activity in the mouse tail suspension test.

分子量

309.83

Formula

C20H20ClN
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

JNJ-7925476 hydrochloride 相关分类

  • 摩尔计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

JNJ-7925476109085-56-5JNJ7925476JNJ 7925476OthersInhibitorinhibitorinhibit

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目录号：
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