1. Cell Cycle/DNA Damage Apoptosis
  2. G-quadruplex Apoptosis
  3. L5-DA

L5-DA 是一种 G-四链体 (G4) 配体,选择性稳定 G4s。L5-DA 对 HeLa 细胞具有显著的细胞毒性 (IC50=4.3 μM)。L5-DA 稳定 HeLa 细胞中的 G4s,诱导细胞凋亡 (apoptosis) 和细胞周期阻滞。

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L5-DA Chemical Structure

L5-DA Chemical Structure

CAS No. : 2986876-41-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

L5-DA is a G-quadruplex (G4) ligand and selectively stabilized for G4s over ds26. L5-DA exhibits significant cytotoxicity against HeLa cells (IC50=4.3 μM). L5-DA stabilizes G4s in HeLa cells, induces apoptosis, and cell cycle arrest[1].

分子量

534.65

Formula

C32H34N6O2

CAS 号
性状

固体

颜色

Light yellow to yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
L5-DA
目录号:
HY-144712
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