2. Cell Cycle/DNA Damage
  3. CDK
  4. LDC3140

LDC3140 是一种选择性 CDK7 抑制剂 (IC50<5 nM)，通过抑制 CDK7 的活性，影响细胞周期的调控，导致细胞周期停滞，进而抑制肿瘤细胞的增殖。LDC3140 可用于癌症治疗领域的研究。

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LDC3140 Chemical Structure

LDC3140 Chemical Structure

CAS No. : 1453833-30-1

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LDC3140 相关抗体

Top Publications Citing Use of Products

查看 CDK 亚型特异性产品:

查看所有亚型
CDK1 CDK2 CDK3 CDK4 CDK5 CDK6 CDK7 CDK8 CDK9 CDK11 CDK12 CDK13 CDK14 CDK16 CDK19 CDC CLK Pho85

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LDC3140 is a selective CDK7 inhibitor (IC50<5 nM). By inhibiting the activity of CDK7, LDC3140 affects the regulation of the cell cycle, leading to cell cycle arrest and thus inhibiting the proliferation of tumor cells. LDC3140 can be used in the research of cancer treatment[1].

IC50 & Target[1]

CDK7

<5 nM (IC50)

分子量

423.55

Formula

C23H33N7O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LDC3140 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LDC31401453833-30-1LDC 3140LDC-3140CDKCyclin dependent kinaseSelective inhibitor of cell cycletumor proliferationcancerCDK7Inhibitorinhibitorinhibit

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产品名称：
LDC3140
目录号：
HY-18969
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