2. Antibody-drug Conjugate/ADC Related
  3. Drug-Linker Conjugates for ADC
  4. Mal-Val-Ala-PAB-N(SO2Me)-Exatecan

Mal-Val-Ala-PAB-N(SO2Me)-Exatecan 

目录号: HY-159072
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摩尔计算器

Mal-Val-Ala-PAB-N(SO2Me)-Exatecan (Compound LE14) 是 ADC 毒素 Exatecan (HY-13631) 和连接子 Mal-Val-Ala-PAB-N(SO2Me) 的偶联物。Mal-Val-Ala-PAB-N(SO2Me)-Exatecan 可用于合成 ADC FZ-AD005。FZ-AD005 是一种靶向 delta 样配体 3 (DLL3, KD=58.3 pM) 的 ADC，对 SCLC 癌症具有抗肿瘤活性。

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Mal-Val-Ala-PAB-N(SO2Me)-Exatecan Chemical Structure

Mal-Val-Ala-PAB-N(SO2Me)-Exatecan Chemical Structure

CAS No. : 2575682-08-3

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Mal-Val-Ala-PAB-N(SO2Me)-Exatecan 相关抗体

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生物活性

Mal-Val-Ala-PAB-N(SO2Me)-Exatecan (Compound LE14) is a conjugate of an ADC toxin Exatecan (HY-13631) and a linker Mal-Val-Ala-PAB-N(SO2Me). Mal-Val-Ala-PAB-N(SO2Me)-Exatecan can be used for synthesis of ADC FZ-AD005. FZ-AD005 is a delta-like ligand 3 (DLL3, KD=58.3 pM) targeting ADC, that exhibits antitumor efficacy against SCLC cancer[1][2].

分子量

1141.22

Formula

C56H65FN8O15S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Mal-Val-Ala-PAB-N(SO2Me)-Exatecan 相关分类

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Keywords:

Mal-Val-Ala-PAB-N(SO2Me)-Exatecan2575682-08-3Drug-Linker Conjugates for ADCSCLCsmall-cell lung cancerRovalpituzumab tesirineRova-Tcynomolgus monkeyNCI-H889NCI-H82NCI-H660LU5236NCI-H1105DMS 53DMS 79 NCI-H2227neuroendocrine prostate cancerNOD/SCID mouseInhibitorinhibitorinhibit

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