2. Academic Validation
  3. Illudinic acid, a novel illudane sesquiterpene antibiotic

Illudinic acid, a novel illudane sesquiterpene antibiotic

  • J Nat Prod. 1997 Feb;60(2):188-90. doi: 10.1021/np960596x.
C Dufresne 1,  K Young,  F Pelaez,  A Gonzalez del Val,  D Valentino,  A Graham,  G Platas,  A Bernard,  D Zink
Affiliations

Affiliation

  • 1 Merck Research Laboratories, Rahway, New Jersey 07065, USA. claude_dufresne@merck.com
PMID: 9051915 DOI: 10.1021/np960596x
Abstract

A novel illudane sesquiterpene Antibiotic (1) with activity against methicillin-resistant Staphylococcus aureus (MRSA), has been isolated. Its MIC against MRSA was found to be 16 micrograms/mL. It also shows L-1210 cytotoxicity with an IC50 of 10-15 micrograms/mL.

Figures
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z