1. Autophagy Metabolic Enzyme/Protease
  2. Autophagy HMG-CoA Reductase (HMGCR) Endogenous Metabolite
  3. Meglutol-d3

Meglutol-d3  (Synonyms: Dicrotalic acid-d3; 3-Hydroxy-3-methylglutaric acid-d3)

目录号: HY-B1189S 纯度: 98.04%
COA 产品使用指南

Meglutol-d3 是 Meglutol 的氘代物。 Meglutol是一种抗血脂剂, 降低胆固醇, 甘油三酯, 及血清β-脂蛋白和磷脂, 并抑制羟甲基戊二酰辅酶A还原酶活性, 这是在胆固醇生物合成中的限速酶。

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Meglutol-d<sub>3</sub> Chemical Structure

Meglutol-d3 Chemical Structure

CAS No. : 59060-36-5

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5 mg ¥1050
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10 mg ¥1700
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Other Forms of Meglutol-d3:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Meglutol-d3 is the deuterium labeled Meglutol[1]. Meglutol is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids, and inhibits the activity of hydroxymethylglutarryl CoA reductases, which is the rate limiting enzyme in the biosynthesis of cholesterol.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

165.16

Formula

C6H7D3O5

CAS 号
非标记 CAS

503-49-1

性状

固体

颜色

White to off-white

中文名称

美格鲁托-d3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号:
HY-B1189S
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